Evidence map›Paper›PMID 28576853›Full record

ArticlePhysiological reports2017

Myocardial apoptosis and mesenchymal stem cells with acute exercise.

Maria F Arisi, Erica N Chirico, Roxanne Sebeny, Geetha Muthukumaran, Anbin Mu, Bart C De Jonghe, Kenneth B Margulies, Joseph R Libonati

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Maria F ArisiSchool of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania.
Erica N ChiricoCooper Medical School, Rowan University, Camden, New Jersey.
Roxanne SebenySchool of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania.
Geetha MuthukumaranSchool of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania.
Anbin MuPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Bart C De JongheSchool of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania.
Kenneth B MarguliesCooper Medical School, Rowan University, Camden, New Jersey.
Joseph R LibonatiSchool of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania jlibonat@nursing.upenn.edu.
University of Pennsylvania · USCooper Medical School of Rowan University · US

Funding

Neural Mechanisms of Nausea, Vomiting, and Energy DysregulationR01DK112812 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI Bart C DE JONGHE, MATTHEW R HAYES · 2017 to 2026
$4.4M
NIDDK NIH HHS R01 DK112812
6 · The paper itself

Abstract

Aerobic exercise confers many health benefits. However, numerous reports have shown that acute aerobic exercise can injure the heart. We tested the general hypothesis that acute moderate-intensity exercise in rodents induces cardiomyocyte damage and stimulates mesenchymal stem cells (MSCs) to increase paracrine-mediated protective effects on cardiomyocytes. A single session of treadmill running (13 m/min, 0% grade, for 45 min) in untrained C57BL/6 male mice (

Indexed as

ApoptosisPhysical Conditioning, AnimalAnimalsCatecholaminesCell ProliferationCells, CulturedChemotaxisMaleMesenchymal Stem CellsMiceMice, Inbred C57BLMyocytes, CardiacRatsStress, PhysiologicalCatecholaminesAcute exerciseapoptosisheartmesenchymal stem cells

Identifiers

PMID28576853
PMCPMC5471436
OpenAlexW2621110653

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.