Evidence map›Paper›PMID 28576827›Full record

ArticleThe Journal of biological chemistry2017

The transcriptional repressor GATAD2B mediates progesterone receptor suppression of myometrial contractile gene expression.

Chien-Cheng Chen, Alina P Montalbano, Imran Hussain, Wan-Ru Lee, Carole R Mendelson

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Progesterone and estrogen regulate NALCN expression in human myometrial smooth muscle cells.American journal of physiology. Endocrinology and metabolism · 2020
    Article
  9. Article
  10. Review
  11. Progesterone Receptor Regulation of Uterine Adaptation for Pregnancy.Trends in endocrinology and metabolism: TEM · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chien-Cheng ChenDepartment of Biochemistry and the Department of Obstetrics and Gynecology, North Texas March of Dimes Birth Defects Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9038.
Alina P MontalbanoDepartment of Biochemistry and the Department of Obstetrics and Gynecology, North Texas March of Dimes Birth Defects Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9038.
Imran HussainDepartment of Biochemistry and the Department of Obstetrics and Gynecology, North Texas March of Dimes Birth Defects Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9038.
Wan-Ru LeeDepartment of Biochemistry and the Department of Obstetrics and Gynecology, North Texas March of Dimes Birth Defects Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9038.
Carole R MendelsonDepartment of Biochemistry and the Department of Obstetrics and Gynecology, North Texas March of Dimes Birth Defects Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9038. Electronic address: carole.mendelson@utsouthwestern.edu.
March of Dimes · USSouthwestern Medical Center · US

Funding

TRANSCRIPTIONAL REGULATION OF CERVICAL COMPETENCE DURING PREGNANCYP01HD011149 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI MENDELSON, CAROLE R · 1998 to 2015
$17.7M
Molecular and Genomic Mechanisms in the Biology of Pregnancy and ParturitionP01HD087150 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI MAHENDROO, MALA S. · 2017 to 2021
$6.7M
NICHD NIH HHS P01 HD011149NICHD NIH HHS P01 HD087150
6 · The paper itself

Abstract

The mechanisms whereby progesterone (P

Indexed as

Down-RegulationAnimalsCells, CulturedCyclooxygenase 2FemaleGATA Transcription FactorsHEK293 CellsHumansInterleukin-8MiceMyometriumProgesteroneReceptors, ProgesteroneRepressor ProteinsUterine ContractionCyclooxygenase 2GATAD2B protein, humanGATA Transcription FactorsInterleukin-8ProgesteronePTGS2 protein, humanReceptors, ProgesteroneRepressor Proteinsgene expressioninflammationnuclear receptorprogesteronetranscription corepressor

Identifiers

PMID28576827
PMCPMC5535031
OpenAlexW2621031549

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.