Evidence map›Paper›PMID 28576736›Full record

Trial reportThe Journal of investigative dermatology2017

Oral Vitamin D Rapidly Attenuates Inflammation from Sunburn: An Interventional Study.

Jeffrey F Scott, Lopa M Das, Sayeeda Ahsanuddin, Yuqi Qiu, Amy M Binko, Zachary P Traylor, Sara M Debanne, Kevin D Cooper, Rebecca Boxer, Kurt Q Lu

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of investigative dermatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 92 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Review
  7. The potential role of 1,25(OH)Journal of inflammation (London, England) · 2025
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Vitamin D and COVID-19: where are we now?Postgraduate medicine · 2023
    Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. The Impact of Vitamin D on Skin Aging.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Jeffrey F ScottDepartment of Dermatology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Lopa M DasDepartment of Dermatology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Sayeeda AhsanuddinDepartment of Dermatology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Yuqi QiuDepartment of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, USA.
Amy M BinkoDepartment of Dermatology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Zachary P TraylorDepartment of Dermatology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Sara M DebanneDepartment of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, USA.
Kevin D CooperDepartment of Dermatology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA; Department of Dermatology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Rebecca BoxerDepartment of Medicine, Division of Geriatrics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Kurt Q LuDepartment of Dermatology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA; Department of Dermatology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA. Electronic address: kql1@case.edu.
Case Western Reserve University · USUniversity Hospitals of Cleveland · USUniversity School · USUniversity of Colorado Anschutz Medical Campus · US

Funding

Vitamin D endocrine system and Protection Against Skin TumorlgenesisP30AR039750 · NIAMS · CASE WESTERN RESERVE UNIVERSITY · PI COOPER, KEVIN D · 1988 to 2015
$9.1M
Amelioration of Vesicant-Induced Skin Injury by High Dose 25-Hydroxyvitamin DU01AR064144 · NIAMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LU, KURT · 2012 to 2016
$4.2M
TRAINING IN INVESTIGATIVE AND MOLECULAR DERMATOLOGYT32AR007569 · NIAMS · CASE WESTERN RESERVE UNIVERSITY · PI COOPER, KEVIN D · 1991 to 2019
$2.7M
NIAMS NIH HHS P30 AR039750NIAMS NIH HHS T32 AR007569NIAMS NIH HHS U01 AR064144
6 · The paper itself

Abstract

The diverse immunomodulatory effects of vitamin D are increasingly being recognized. However, the ability of oral vitamin D to modulate acute inflammation in vivo has not been established in humans. In a double-blinded, placebo-controlled interventional trial, 20 healthy adults were randomized to receive either placebo or a high dose of vitamin D

Indexed as

Administration, OralAdultCholecalciferolDose-Response Relationship, DrugDouble-Blind MethodFemaleFollow-Up StudiesHumansInflammationMaleMiddle AgedSkinSunburnTime FactorsTreatment OutcomeVitaminsCholecalciferolVitamins

Identifiers

PMID28576736
PMCPMC5610950
OpenAlexW2605783229

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.