Evidence map›Paper›PMID 28576734›Full record

Trial reportContemporary clinical trials2017

Protocol for the MATCH study (Mindfulness and Tai Chi for cancer health): A preference-based multi-site randomized comparative effectiveness trial (CET) of Mindfulness-Based Cancer Recovery (MBCR) vs. Tai Chi/Qigong (TCQ) for cancer survivors.

Linda E Carlson, Erin L Zelinski, Michael Speca, Lynda G Balneaves, Jennifer M Jones, Daniel Santa Mina, Peter M Wayne, Tavis S Campbell, Janine Giese-Davis, Peter Faris and 10 more

Registry-linked trialOpen access · greenAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Contemporary clinical trials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04019301 (Caring for Caregivers With Mind-body Exercise), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04019301 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Caring for Caregivers With Mind-body Exercise

TypeinterventionalSponsorUniversity of HoustonRan2019 to 2022Enrolled47ConditionsCaregiver Distress, Physical Function, Quality of LifeArmsBaduanjin Qigong, Community-based, Baduanjin Qigong, Internet-based
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Severe fatigue after treatment for childhood cancer.The Cochrane database of systematic reviews · 2020
    Pooled it
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  4. The Science of Tai Chi andJournal of integrative and complementary medicine · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 8 institutions in 2 countries.

Linda E CarlsonDepartment of Oncology, University of Calgary, Calgary, AB, Canada; Cancer Control Board, Alberta Health Services, AB, Canada. Electronic address: l.carlson@ucalgary.ca.
Erin L ZelinskiDepartment of Oncology, University of Calgary, Calgary, AB, Canada; Cancer Control Board, Alberta Health Services, AB, Canada.
Michael SpecaDepartment of Oncology, University of Calgary, Calgary, AB, Canada; Cancer Control Board, Alberta Health Services, AB, Canada.
Lynda G BalneavesCollege of Nursing, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
Jennifer M JonesFaculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON, Canada.
Daniel Santa MinaFaculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON, Canada.
Peter M WayneOsher Center for Integrative Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
Tavis S CampbellDepartment of Psychology, University of Calgary, Calgary, AB, Canada.
Janine Giese-DavisDepartment of Oncology, University of Calgary, Calgary, AB, Canada; Cancer Control Board, Alberta Health Services, AB, Canada.
Peter FarisCentre for Advancement of Health, Alberta Health Services, AB, Canada.
Jennifer ZwickerSchool of Public Policy, University of Calgary, Calgary, AB, Canada.
Kamala PatelDepartment of Immunology, University of Calgary, Calgary, AB, Canada.
Tara L BeattieDepartment of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada.
Steve ColeDepartment of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Kirsti ToivonenDepartment of Psychology, University of Calgary, Calgary, AB, Canada.
Jill NationDepartment of Oncology, University of Calgary, Calgary, AB, Canada.
Philip PengDepartment of Anesthesia, University of Toronto, ON, Canada.
Bruce ThongDepartment of Athletics and Recreation, McMaster University, Hamilton, ON, Canada.
Raimond WongDepartment of Oncology, McMaster University, Hamilton, ON, Canada; Department of Medicine, McMaster University, Hamilton, ON, Canada.
Sunita VohraDepartment of Pediatrics, Faculty of Medicine and Dentistry, Integrative Health Institute, University of Alberta, Edmonton, AB, Canada.
University of Calgary · CAAlberta Health Services · CAUniversity of Toronto · CAMcMaster University · CABrigham and Women's Hospital · USUniversity of Alberta · CAUniversity of California, Los Angeles · USUniversity of Manitoba · CA

Funding

Mentoring and research in mind-body and integrative therapiesK24AT009282 · NCCIH · BRIGHAM AND WOMEN'S HOSPITAL · PI WAYNE, PETER MICHAEL · 2017 to 2021
$834k
NCCIH NIH HHS K24 AT009282
6 · The paper itself

Abstract

purposeA growing number of cancer survivors suffer high levels of distress, depression and stress, as well as sleep disturbance, pain and fatigue. Two different mind-body interventions helpful for treating these problems are Mindfulness-Based Cancer Recovery (MBCR) and Tai Chi/Qigong (TCQ). However, while both interventions show efficacy compared to usual care, they have never been evaluated in the same study or directly compared. This study will be the first to incorporate innovative design features including patient choice while evaluating two interventions to treat distressed cancer survivors. It will also allow for secondary analyses of which program best targets specific symptoms in particular groups of survivors, based on preferences and baseline characteristics. METHODS AND SIGNIFICANCE: The design is a preference-based multi-site randomized comparative effectiveness trial. Participants (N=600) with a preference for either MBCR or TCQ will receive their preferred intervention; while those without a preference will be randomized into either intervention. Further, within the preference and non-preference groups, participants will be randomized into immediate intervention or wait-list control. Total mood disturbance on the Profile of mood states (POMS) post-intervention is the primary outcome. Other measures taken pre- and post-intervention and at 6-month follow-up include quality of life, psychological functioning, cancer-related symptoms and physical functioning. Exploratory analyses investigate biomarkers (cortisol, cytokines, blood pressure/Heart Rate Variability, telomere length, gene expression), which may uncover potentially important effects on key biological regulatory and antineoplastic functions. Health economic measures will determine potential savings to the health system.

Indexed as

NeoplasmsQigongQuality of LifeStress, PsychologicalTai JiAdaptation, PsychologicalAdultCancer SurvivorsFemaleHumansMaleMiddle AgedMindfulnessPatient PreferencePsychological TechniquesPsychotherapy, GroupBiomarkersCancer survivorsClinical trialExerciseMindfulnessMood disturbancePreference trialQigongQuality of lifeStressTai ChiYoga

Identifiers

PMID28576734
PMCPMC5639905
OpenAlexW2618538978

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.