ArticleClinical lung cancer2017
Impact of Omission of Intrapulmonary Lymph Node Retrieval on Outcome Evaluation of Lung Cancer Patients Without Lymph Node Metastasis: A Propensity Score Matching Analysis.
Article in Clinical lung cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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15 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Prognostic value of different N1 lymph node zones in pN1M0 non-small cell lung cancer: a systematic review and meta-analysis.Scientific reports · 2021Pooled it
- N1 Staging in Non-Small Cell Lung Cancer: Current Situation, Limitations, and the Importance of Peripheral Nodal Assessment.Cancers · 2026Review
- Standardized intrapulmonary lymph node dissection in lung cancer specimens: A national Colombian analysis.JTCVS open · 2024Article
- Thoracoscopic right middle lobe subsegmentectomy: A single-center, retrospective review.JTCVS techniques · 2022Article
- The impacts of isolated N1 lymph nodes metastasis on prognosis in non-small cell lung cancer: A single-center experience.Turk gogus kalp damar cerrahisi dergisi · 2022Article
- A standard for hilar and intrapulmonary lymph node dissection and pathological examination in early non-small cell lung cancer.Translational lung cancer research · 2021Article
- The impact of an N1 lymph node examination in patients with early-stage non-small cell lung cancer: a retrospective cohort study.Journal of thoracic disease · 2021Article
- Spanish Lung Cancer Group SCAT trial: surgical audit to lymph node assessment based on IASLC recommendations.Translational lung cancer research · 2021Article
- Skip metastasis in mediastinal lymph node is a favorable prognostic factor in N2 lung cancer patients: a meta-analysis.Annals of translational medicine · 2021Article
- Analysis of Segmental Lymph Node Metastasis and Clinical Features in cT1N0M0 Lung Adenocarcinoma.BioMed research international · 2020Article
- Value of N1 Lymph Node Examination in the Prognosis of Patients With pT1-3N0M0 Non-Small Cell Lung Cancer.Frontiers in oncology · 2020Article
- Adjuvant chemotherapy may improve outcome of patients with non-small-cell lung cancer with metastasis of intrapulmonary lymph nodes after systematic dissection of N1 nodes.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2018Article
- Perspective and clinical relevance of intrapulmonary lymph node retrieval: response to the editorial by Tantraworasin and colleagues and the editorial by Marc Riquet and colleagues.Journal of thoracic disease · 2018Article
- Role of intrapulmonary lymph node retrieval for pathological examination in resectable non-small cell lung cancer.Journal of thoracic disease · 2017Article
- Pathologic N1 disease in lung cancer: the segmental and subsegmental lymph nodes.Journal of thoracic disease · 2017Article
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9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionClinical practice of retrieval of segmental (station 13) and subsegmental (station 14) lymph nodes for pathologic examination varies during lung cancer surgery. This study aimed to evaluate whether omitting retrieval of nodes from stations 13 and 14 could affect outcome evaluation for patients with pN0 non-small-cell lung cancer (NSCLC).
methodsThis retrospective study analyzed 442 patients with NSCLC who were treated with both R0 resection and systematic mediastinal lymphadenectomy with pathologically confirmed stage pN0 NSCLC. The study group included patients in whom N1 nodes including stations 10 to 14 were investigated, and the control group included patients in whom stations 10 to 12 only were investigated. Clinical and pathologic parameters of the groups were balanced by propensity score matching, and oncologic outcomes were assessed by the log-rank test.
resultsA total of 435 cases were included in the final analysis (170 in the study group and 265 in the control group). In the study group, a mean ± SD of 5.0 ± 3.0 nodes per case were collected from nodes 13 and 14. After propensity score matching, 143 cases were included in each group. Overall and disease-free survival improved in the study group compared to the control group (P = .027 and P = .021, respectively). T staging and intrapulmonary node collection were prognostic factors for pN0 cases.
conclusionInferior oncologic outcomes of pN0 cases without intrapulmonary node retrieval suggest that the procedure of intrapulmonary lymph node retrieval may play a role in outcome evaluation for pN0 NSCLC patients.
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