Evidence map›Paper›PMID 28576296›Full record

ArticleNursing outlook

Biological determinants of health: Genes, microbes, and metabolism exemplars of nursing science.

Erin P Ferranti, Ruth Grossmann, Angela Starkweather, Margaret Heitkemper

Abstract read
In one paragraph

Article in Nursing outlook. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. [Status Quo and Prospects of Research on Precision Nursing of Life-Cycle Health and Disease].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023
    Review
  3. Article
  4. Review
  5. Establishing the Omics Nursing Science & Education Network.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2020
    Article
  6. Precision health: A nursing perspective.International journal of nursing sciences · 2020
    Review
  7. Cardiovascular and Stroke Nursing Council Science in Review.Journal of the American Heart Association · 2019
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Erin P FerrantiNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA.
Ruth GrossmannCollege of Nursing, University of Iowa, Iowa City, IA.
Angela StarkweatherCenter for Advancement in Managing Pain and P20 Center for Accelerating Precision Pain Self-Management, University of Connecticut School of Nursing, Storrs, CT.
Margaret HeitkemperDepartment of Biobehavioral Nursing and Health Informatics, University of Washington School of Nursing, Seattle, WA. Electronic address: heit@uw.edu.

Funding

Pilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI Carmen Joseph Marsit · 2013 to 2026
$22.6M
NURSING MANAGEMENT OF IBS--IMPROVING OUTCOMESR01NR004142 · NINR · UNIVERSITY OF WASHINGTON · PI HEITKEMPER, MARGARET MCLEAN · 1996 to 2011
$5.5M
Emory University BIRCWH ProgramK12HD085850 · NICHD · EMORY UNIVERSITY · PI OFOTOKUN, IGHOVWERHA, STERK, CLAIRE E · 2015 to 2023
$4.4M
Biobehavioral Determinants of the Microbiome and Preterm Birth in Black WomenR01NR014800 · NINR · EMORY UNIVERSITY · PI CORWIN, ELIZABETH JEANNE, DUNLOP, ANNE LANG · 2013 to 2017
$2.8M
Pain Sensitivity in Low Back PainR01NR013932 · NINR · VIRGINIA COMMONWEALTH UNIVERSITY · PI STARKWEATHER, ANGELA RENEE · 2013 to 2015
$1.3M
Metabolomic Biomarkers of a Nutritional Intervention to Prevent Weight GainK01GM109309 · NIGMS · UNIVERSITY OF IOWA · PI GROSSMANN, RUTH ELIZABETH · 2013 to 2016
$619k
NICHD NIH HHS K12 HD085850NIEHS NIH HHS P30 ES019776NIGMS NIH HHS K01 GM109309NINR NIH HHS R01 NR004142NINR NIH HHS R01 NR013932NINR NIH HHS R01 NR014800
6 · The paper itself

Abstract

backgroundIncreasingly, nurse scientists are incorporating "omics" measures (e.g., genomics, transcriptomics, proteomics, and metabolomics) in studies of biologic determinants of health and behavior. The role of omics in nursing science can be conceptualized in several ways: (a) as a portfolio of biological measures (biomarkers) to monitor individual risk, (b) as a set of combined data elements that can generate new knowledge based on large and complex patient data sets, (c) as baseline information that promotes health education and potentially personalized interventions, and (d) as a platform to understand how environmental parameters (e.g., diet) interact with the individual's physiology. PURPOSE: In this article, we provide exemplars of nursing scientists who use omics to better understand specific health conditions.

methodsWe highlight various ongoing nursing research investigations incorporating omics technologies to study chronic pain vulnerability, risk for a pain-related condition, cardiometabolic complications associated with pregnancy, and as biomarkers of response to a dietary intervention. DISCUSSION: Omics technologies add an important dimension to nursing science across many foci of investigation. However, there are also challenges and opportunities for nurse scientists who consider using omics in their research.

conclusionThe integration of omics holds promise for increasing the impact of nursing research and practice on population health outcomes.

Indexed as

BiomarkersGenomicsMetabolomicsPrecision MedicineProteomicsHumansNursing ResearchBiomarkersGenomicsMetabolomicsMetagenomicsPrecision medicine

Identifiers

PMID28576296
PMCPMC5657318

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.