Evidence map›Paper›PMID 28575720›Full record

ReviewCurrent opinion in neurobiology2017

Local aspects of sleep and wakefulness.

Francesca Siclari, Giulio Tononi

Registry-linked trialAbstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04235894 (An Observer Rating Scale of Facial Expression Can Predict Dreaming in Propofol Anesthesia), which is not on this map. Cited by 94 papers.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04235894 completednot on this map

An Observer Rating Scale of Facial Expression Can Predict Dreaming in Propofol Anesthesia

TypeobservationalSponsorOsijek University HospitalRan2016 to 2017Enrolled124ConditionsAnesthesia, Propofol, Drug EffectArmsPropofol
3 · Its place in the literature

Who cites it

94 citing papers in PubMed.

  1. Trial
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  3. Protecting episodic memory after sleep loss: Similar benefits of exercise and naps via distinct neural contributions.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  17. Review
  18. Dreaming conundrum.Journal of sleep research · 2025
    Review
  19. Article
  20. Article

34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Francesca SiclariCenter for Research and Investigation on Sleep (CIRS), Lausanne University Hospital (CHUV) and University of Lausanne, Rue du Bugnon 46, 1011 Lausanne, Switzerland; Department of Psychiatry, University of Wisconsin-Madison, 6001 Research Park Boulevard Madison, WI 53519, USA. Electronic address: francesca.siclari@chuv.ch.
Giulio TononiDepartment of Psychiatry, University of Wisconsin-Madison, 6001 Research Park Boulevard Madison, WI 53519, USA. Electronic address: gtononi@wisc.edu.

Funding

Wisconsin Center for the Neuroscience and Psychophysiology of MeditationP01AT004952 · NCCIH · UNIVERSITY OF WISCONSIN-MADISON · PI DAVIDSON, RICHARD J · 2008 to 2018
$14.7M
Electron Microscopy Core CP01NS083514 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI TONONI, GIULIO · 2014 to 2018
$7.7M
The cost of plasticity: from cells to systemsR01MH099231 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI CIRELLI, CHIARA, TONONI, GIULIO · 2013 to 2017
$3.3M
NCCIH NIH HHS P01 AT004952NIMH NIH HHS R01 MH099231NINDS NIH HHS P01 NS083514
6 · The paper itself

Abstract

Slow waves, the hallmark of NREM (Non Rapid Eye Movement) sleep, are not uniformly distributed across the cortical surface, but can occur locally and asynchronously across brain regions. Their regional distribution and amplitude is affected by brain maturation and by time spent awake, mediated in part by experience-dependent changes in synaptic strength. Recent studies have shown that local low-frequency oscillations (<10Hz) can also occur in REM sleep and during wakefulness, leading to region-specific cognitive errors. Local decreases and increases of slow wave activity in posterior brain regions have been linked to the occurrence of dreaming and to unconscious sleep, respectively. Finally, the coexistence of local sleep-like and wake-like patterns in different brain areas is characteristic of several sleep disorders and may offer insights into these conditions.

Indexed as

BrainBrain WavesHumansSleepSleep, REMWakefulness

Identifiers

PMID28575720
PMCPMC6445546

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.