ArticleSocial cognitive and affective neuroscience2017
Like mother like daughter: putamen activation as a mechanism underlying intergenerational risk for depression.
Article in Social cognitive and affective neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Risk-taking in the human brain: An activation likelihood estimation meta-analysis of the balloon analog risk task (BART).Human brain mapping · 2022Pooled it
- Early deprivation disruption of associative learning is a developmental pathway to depression and social problems.Nature communications · 2018Trial
- Family-Level Brain Pattern Similarities and Their Clinical Significance in Young Offspring of Individuals With Psychotic Disorders.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Intergenerational neuroimaging's present and future: Considering sex as a biological variable to enhance knowledge of brain development through parent-offspring similarity.Developmental cognitive neuroscience · 2025Review
- Attenuated cognitive control network connectivity as a mechanism in mother-daughter intergenerational transmission of depression: a preliminary study.Scientific reports · 2025Article
- Associations between perceived excessive maternal control in childhood, well-being, and dorsal striatum volume in older adults.Scientific reports · 2025Article
- Siblings' similarity in neural responses to loss reflects mechanisms of familial transmission for depression.Journal of psychiatric research · 2025Article
- Young Children of Mothers with a History of Depression Show Attention Bias to Sad Faces: An Eye-tracking Study.Research on child and adolescent psychopathology · 2024Article
- Intergenerational transmission of brain structure and function in humans: a narrative review of designs, methods, and findings.Brain structure & function · 2024Review
- From mother to child: How intergenerational transfer is reflected in similarity of corticolimbic brain structure and mental health.Developmental cognitive neuroscience · 2023Article
- Specificity of associations between parental psychopathology and offspring brain structure.Psychiatry research. Neuroimaging · 2023Article
- Transmit Radiant Individuality to Offspring (TRIO) study: investigating intergenerational transmission effects on brain development.Frontiers in psychiatry · 2023Article
- Intrinsic Connectivity and Family Dynamics: Striatolimbic Markers of Risk and Resilience in Youth at Familial Risk for Mood Disorders.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022Article
- Mother-child similarity in brain morphology: A comparison of structural characteristics of the brain's reading network.Developmental cognitive neuroscience · 2022Article
- Neural Correlates of Positive Emotion Processing That Distinguish Healthy Youths at Familial Risk for Bipolar Versus Major Depressive Disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2021Article
- Interactions between methodological and interindividual variability: How Monetary Incentive Delay (MID) task contrast maps vary and impact associations with behavior.Brain and behavior · 2021Article
- A Social Affective Neuroscience Model of Risk and Resilience in Adolescent Depression: Preliminary Evidence and Application to Sexual and Gender Minority Adolescents.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2021Review
- Smaller caudate gray matter volume is associated with greater implicit suicidal ideation in depressed adolescents.Journal of affective disorders · 2021Article
- Concordance in parent and offspring cortico-basal ganglia white matter connectivity varies by parental history of major depressive disorder and early parental care.Social cognitive and affective neuroscience · 2020Article
- TEAMwork: Testing Emotional Attunement and Mutuality During Parent-Adolescent fMRI.Frontiers in human neuroscience · 2020Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Having a depressed mother is one of the strongest predictors for developing depression in adolescence. Given the role of aberrant reward processing in the onset and maintenance of depression, we examined the association between mothers' and their daughters' neural response to the anticipation of reward and loss. Fifteen non-depressed mothers with a history of recurrent depression and their never-disordered daughters, and 23 mothers without past or current depression and their never-disordered daughters, underwent functional magnetic resonance imaging while performing the monetary incentive delay task. To assess mother-daughter concordance, we first identified ROIs involved in the anticipation of reward and loss across all mother-daughter pairs. Within each of these ROIs, we examined the association between mothers' and daughters' neural response, and the interaction between group status and mothers' neural response in predicting daughters' neural response. We found a significant association between mothers' and daughters' putamen response to the anticipation of loss, regardless of mother's depression history. Furthermore, pubertal stage moderated the association between mother-daughter putamen concordance. Our findings suggest a unique role of the putamen in the maternal transmission of reward learning and have important implications for understanding disorders characterized by disturbances in reward learning and processing, such as major depression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.