ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2017
Chest Radiograph Findings in Childhood Pneumonia Cases From the Multisite PERCH Study.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 4 of them syntheses that pooled it.
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Who cites it
42 citing papers in PubMed, 4 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- What are the risk factors for death among children with pneumonia in low- and middle-income countries? A systematic review.Journal of global health · 2023Pooled it
- Short-Course vs Long-Course Antibiotic Therapy for Children With Nonsevere Community-Acquired Pneumonia: A Systematic Review and Meta-analysis.JAMA pediatrics · 2022Pooled it
- Pediatric chest radiograph interpretation: how far has artificial intelligence come? A systematic literature review.Pediatric radiology · 2022Pooled it
- Prevalence of hypoxaemia in children with pneumonia in low-income and middle-income countries: a systematic review and meta-analysis.The Lancet. Global health · 2022Pooled it
- Lung ultrasound and procalcitonin, improving antibiotic management and avoiding radiation exposure in pediatric critical patients with bacterial pneumonia: a randomized clinical trial.European journal of medical research · 2024Trial
- Trial
- Malawian children with chest-indrawing pneumonia with and without comorbidities or danger signs.Journal of global health · 2021Trial
- Severe lower respiratory tract infections are associated with human adenovirus in hospitalised children in a high HIV prevalence area.African journal of thoracic and critical care medicine · 2024Article
- Association of Radiology Findings with Etiology of Community Acquired Pneumonia among Children.The Journal of pediatrics · 2023Article
- Clinical algorithm reduces antibiotic use among children presenting with respiratory symptoms to hospital in central Vietnam.Pneumonia (Nathan Qld.) · 2023Article
- Cardiovascular abnormalities in chest radiographs of children with pneumonia, Uganda.Bulletin of the World Health Organization · 2023Article
- The utility of chest x-ray and lung ultrasound in the management of infants and children presenting with severe pneumonia in low-and middle-income countries: A pragmatic scoping review.Journal of global health · 2022Article
- Article
- Digitally recorded and remotely classified lung auscultation compared with conventional stethoscope classifications among children aged 1-59 months enrolled in the Pneumonia Etiology Research for Child Health (PERCH) case-control study.BMJ open respiratory research · 2022Article
- Chest radiography in children aged 2-59 months enrolled in the Innovative Treatments in Pneumonia (ITIP) project in Lilongwe Malawi: a secondary analysis.BMC pediatrics · 2022Article
- Article
- Association of Clinical Signs, Host Biomarkers and Etiology With Radiological Pneumonia in Bhutanese Children.Global pediatric health · 2022Article
- Sentinel surveillance for bacterial pneumonia and meningitis in children under the age of 5 in a tertiary pediatric hospital in Colombia - 2016.Biomedica : revista del Instituto Nacional de Salud · 2021Article
- Malawian children with fast-breathing pneumonia with and without comorbidities.Pneumonia (Nathan Qld.) · 2021Article
- Epidemiology of Hypoxic Community-Acquired Pneumonia in Children Under 5 Years of Age: An Observational Study in Northern India.Frontiers in pediatrics · 2021Article
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36 authors at 19 institutions in 11 countries.
Funding
Abstract
BACKGROUND.: Chest radiographs (CXRs) are frequently used to assess pneumonia cases. Variations in CXR appearances between epidemiological settings and their correlation with clinical signs are not well documented. METHODS.: The Pneumonia Etiology Research for Child Health project enrolled 4232 cases of hospitalized World Health Organization (WHO)-defined severe and very severe pneumonia from 9 sites in 7 countries (Bangladesh, the Gambia, Kenya, Mali, South Africa, Thailand, and Zambia). At admission, each case underwent a standardized assessment of clinical signs and pneumonia risk factors by trained health personnel, and a CXR was taken that was interpreted using the standardized WHO methodology. CXRs were categorized as abnormal (consolidation and/or other infiltrate), normal, or uninterpretable. RESULTS.: CXRs were interpretable in 3587 (85%) cases, of which 1935 (54%) were abnormal (site range, 35%-64%). Cases with abnormal CXRs were more likely than those with normal CXRs to have hypoxemia (45% vs 26%), crackles (69% vs 62%), tachypnea (85% vs 80%), or fever (20% vs 16%) and less likely to have wheeze (30% vs 38%; all P < .05). CXR consolidation was associated with a higher case fatality ratio at 30-day follow-up (13.5%) compared to other infiltrate (4.7%) or normal (4.9%) CXRs. CONCLUSIONS.: Clinically diagnosed pneumonia cases with abnormal CXRs were more likely to have signs typically associated with pneumonia. However, CXR-normal cases were common, and clinical signs considered indicative of pneumonia were present in substantial proportions of these cases. CXR-consolidation cases represent a group with an increased likelihood of death at 30 days post-discharge.
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