Evidence map›Paper›PMID 28575241›Full record

ArticleDiseases of the esophagus : official journal of the International Society for Diseases of the Esophagus2017

Reduced fitness and physical functioning are long-term sequelae after curative treatment for esophageal cancer: a matched control study.

J A Gannon, E M Guinan, S L Doyle, P Beddy, J V Reynolds, J Hussey

Abstract read
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In one paragraph

Article in Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 6 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 6 syntheses or guidelines pooled it, 63 citations in OpenAlex.

  1. Pooled it
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  4. Cardiopulmonary Exercise Testing in Oesophagogastric Surgery: a Systematic Review.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020
    Pooled it
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  7. Trial
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  12. Clinical mechanism of muscle mass loss during neoadjuvant chemotherapy in older patients with esophageal cancer: a prospective cohort study.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2025
    Article
  13. Factors associated with functional ability in patients with esophageal cancer undergoing chemoradiotherapy: a prospective longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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  17. Health-related quality of life after esophagectomy in patients with esophageal cancer.Esophagus : official journal of the Japan Esophageal Society · 2022
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

J A GannonDiscipline of Physiotherapy, School of Medicine, Trinity College Dublin, Dublin, Ireland.
E M GuinanDiscipline of Physiotherapy, School of Medicine, Trinity College Dublin, Dublin, Ireland.
S L DoyleDiscipline of Physiotherapy, School of Medicine, Trinity College Dublin, Dublin, Ireland.
P BeddyDepartment of Radiology.
J V ReynoldsDepartment of Surgery, St James's Hospital and Trinity College Dublin, Dublin, Ireland.
J HusseyDiscipline of Physiotherapy, School of Medicine, Trinity College Dublin, Dublin, Ireland.
Trinity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reduced physical functioning is common following resections for esophageal cancer; however, objective data on physical performance outcomes in this cohort are rare. The aim of this study was to assess the physical performance and health related quality of life (HRQOL) of disease free survivors and compare findings in a case matched noncancer control group. Twenty-five males (mean (±SD) aged 63 (±6) years) who were over 6 months postesophagectomy and disease-free were compared with 25 controls (60 ± 6 years). Physical functioning was assessed through hand grip strength (dynamometry), exercise capacity (incremental shuttle walk test), physical activity levels (RT3 accelerometer), and body composition (bio-electrical impedance analysis). Health-related quality of life was measured using the EORTC QLQ-C30 questionnaire. Esophageal cancer survivors demonstrated significantly lower fitness (P < 0.001) and time spent in moderate (P < 0.001) and vigorous (P < 0.001) intensity physical activity compared with controls. Global health status and quality of life were similar in both groups (P = 0.245); however, physical and role functioning domains were lower in the cancer survivors (P < 0.001, and P = 0.001, respectively). These data show that disease-free survivors of curative esophageal cancer treatment demonstrate a significant compromise in physical functioning compared with controls, thus highlighting the multiple, complex rehabilitative needs of this cohort.

Indexed as

AgedCase-Control StudiesCohort StudiesEsophageal NeoplasmsEsophagectomyFemaleHand StrengthHealth StatusHumansMaleMiddle AgedPhysical FitnessPostoperative PeriodQuality of LifeTimeTreatment OutcomeBody compositionesophageal neoplasmmotor activityphysical fitnessquality of life

Identifiers

PMID28575241
OpenAlexW2617715456

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.