ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2017
Emergence of Livestock-Associated Methicillin-Resistant Staphylococcus aureus Bloodstream Infections in Denmark.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
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Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Animal sources of antimicrobial-resistant bacterial infections in humans: a systematic review.Epidemiology and infection · 2023Pooled it
- Methicillin-resistant Staphylococcus aureus.Nature reviews. Disease primers · 2026Review
- Genomic and phylogenetic characterization of human-adapted methicillin-resistantMicrobiology spectrum · 2026Article
- Molecular characteristics and pathogenicity-associated phenotypes of methicillin-resistantFrontiers in public health · 2026Article
- From Farm to Fork: Antimicrobial-Resistant Bacterial Pathogens in Livestock Production and the Food Chain.Veterinary sciences · 2025Review
- Review
- Comparative Evaluation of the Antibiotic Resistance Profile ofInternational journal of public health · 2024Article
- Whole-Genome Investigation of Zoonotic Transmission of Livestock-Associated Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2023Article
- Virulence Mechanisms of Staphylococcal Animal Pathogens.International journal of molecular sciences · 2023Review
- Exploring the third-generation tetracycline resistance of multidrug-resistant livestock-associated methicillin-resistant Staphylococcus aureus ST9 across healthcare settings in China.The Journal of antimicrobial chemotherapy · 2023Article
- The Epidemiology of Animal-Associated Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2023Review
- Genome Analysis of Methicillin-Resistant and Methicillin-SusceptibleMicroorganisms · 2023Article
- A review of new emerging livestock-associated methicillin-resistantVeterinary world · 2023Review
- Methicillin-resistantEmerging microbes & infections · 2022Article
- Article
- Antimicrobial Susceptibility Profiles and Molecular Characterisation ofAntibiotics (Basel, Switzerland) · 2022Article
- A Survey of Chinese Pig Farms and Human Healthcare Isolates Reveals Separate Human and Animal Methicillin-Resistant Staphylococcus aureus Populations.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Livestock-associated methicillin-resistantFrontiers in microbiology · 2022Article
- Comparative analysis of genomic characteristics, fitness and virulence of MRSA ST398 and ST9 isolated from China and Germany.Emerging microbes & infections · 2021Article
- Dynamics of the Human Nasal Microbiota and Staphylococcus aureus CC398 Carriage in Pig Truck Drivers across One Workweek.Applied and environmental microbiology · 2021Article
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10 authors.
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Abstract
Background: Livestock-associated methicillin-resistant Staphylococcus aureus clonal complex 398 (LA-MRSA CC398) is causing an increasing number of skin and soft tissue infections (SSTIs) in Denmark and other European countries with industrial pig production. Yet, its impact on MRSA bloodstream infections (BSIs) has not been well studied. Methods: We investigated the clinical epidemiology of all human cases of LA-MRSA CC398 BSI during 2010-2015. Cases of LA-MRSA CC398 BSI were compared to cases of BSI caused by other types of MRSA and cases of SSTI caused by LA-MRSA CC398. Whole-genome sequence analysis was used to assess the phylogenetic relationship among LA-MRSA CC398 isolates from Danish pigs and cases of BSI and SSTI. Results: The number of LA-MRSA CC398 BSIs and SSTIs increased over the years, peaking in 2014, when LA-MRSA CC398 accounted for 16% (7/44) and 21% (211/985) of all MRSA BSIs and SSTIs, corresponding to 1.2 and 37.4 cases of BSI and SSTI per 1000000 person-years, respectively. Most patients with LA-MRSA CC398 BSI had no contact to livestock, although they tended to live in rural areas. LA-MRSA CC398 caused 24.3 BSIs per 1000 SSTIs among people with no livestock contact, which is similar to the ratio observed for other types of MRSA. Whole-genome sequence analysis showed that most of the BSI and SSTI isolates were closely related to Danish pig isolates. Conclusions: This study demonstrates that the increasing number of LA-MRSA CC398 BSIs occurred in parallel with a much larger wave of LA-MRSA CC398 SSTIs and an expanding pig reservoir.
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