Evidence map›Paper›PMID 28575141›Full record

ArticleAge and ageing2017

Objectively measured physical activity and kidney function in older men; a cross-sectional population-based study.

Tessa J Parsons, Claudio Sartini, Sarah Ash, Lucy T Lennon, S Goya Wannamethee, I-Min Lee, Peter H Whincup, Barbara J Jefferis

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Age and ageing, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. The Impact of Sedentary Behavior on Renal Function Decline in 132,123 Middle Aged and Older Adults: A Nationwide Cohort Study.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
  7. Ageing meets kidney disease.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
    Article
  8. Ageing meets kidney disease.Clinical kidney journal · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. The renal molecular clock: broken by aging and restored by exercise.American journal of physiology. Renal physiology · 2019
    Review
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Tessa J ParsonsUCL Department of Primary Care and Population Health, UCL Medical School, London NW3 2PF, UK.
Claudio SartiniUCL Department of Primary Care and Population Health, UCL Medical School, London NW3 2PF, UK.
Sarah AshUCL Department of Primary Care and Population Health, UCL Medical School, London NW3 2PF, UK.
Lucy T LennonUCL Department of Primary Care and Population Health, UCL Medical School, London NW3 2PF, UK.
S Goya WannametheeUCL Department of Primary Care and Population Health, UCL Medical School, London NW3 2PF, UK.
I-Min LeeBrigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, USA.
Peter H WhincupPopulation Health Research Institute, St George's University of London, Cranmer Terrace, London SW17 0RE, UK.
Barbara J JefferisUCL Department of Primary Care and Population Health, UCL Medical School, London NW3 2PF, UK.
University College London · GBBrigham and Women's Hospital · USSt George's, University of London · GB

Funding

British Heart Foundation PG/09/024/26857British Heart Foundation PG/13/86/30546British Heart Foundation RG/08/013/25942British Heart Foundation RG/13/16/30528Department of Health PDF-2010-03-23
6 · The paper itself

Abstract

Background: kidney function declines in older adults and physical activity levels are low. We investigated whether higher levels of physical activity and lower levels of sedentary behaviour were associated with lower odds of low kidney function in older men. Methods: cross-sectional study of 1,352 men from the British Regional Heart Study, mean (standard deviation) age 78.5 (4.6) year. Physical activity and sedentary behaviour were measured using Actigraph GT3X accelerometers. Kidney function was measured by estimated Glomerular filtration rate (eGFR) using the chronic kidney disease-EPI creatinine-cystatin equation. Associations between physical (in)activity and kidney function were investigated using regression models. Results: higher levels of physical activity and lower levels of sedentary behaviour were associated with reduced odds ratios (ORs) for lower eGFR (<45 versus ≥45 ml/min per 1.73 m2) after adjustment for covariates. Each additional 1,000 steps, 30 min of light physical activity and 10 min of moderate/vigorous physical activity per day were associated with a lower odds (95% confidence interval (CI)) of a low eGFR; OR 0.81 (0.73, 0.91), OR 0.87 (0.78, 0.97) and OR 0.84 (0.76, 0.92), respectively. Each additional 30 min of sedentary behaviour per day was associated with a higher odds of a low eGFR (1.16 95% CI 1.06, 1.27). Associations between moderate/vigorous physical activity and lower kidney function persisted after adjustment for light physical activity or sedentary behaviour. Conclusion: physical activity is associated with kidney function in older men and could be of public health importance in this group who are at increased risk of poor kidney function and low physical activity. More evidence is needed on whether the association is causal.

Indexed as

ExerciseGlomerular Filtration RateRisk Reduction BehaviorActigraphyAgedAged, 80 and overAge FactorsAgingBiomarkersCreatinineCross-Sectional StudiesCystatin CFitness TrackersHumansKidneyKidney DiseasesBiomarkersCreatinineCST3 protein, humanCystatin Cglomerular filtration ratekidney functionolder peoplephysical activitysedentary behaviour

Identifiers

PMID28575141
PMCPMC5860422
OpenAlexW2620755997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.