Evidence map›Paper›PMID 28575034›Full record

ArticlePLoS neglected tropical diseases2017

Ebola virus disease contact tracing activities, lessons learned and best practices during the Duport Road outbreak in Monrovia, Liberia, November 2015.

Caitlin M Wolfe, Esther L Hamblion, Jacqueline Schulte, Parker Williams, Augustine Koryon, Jonathan Enders, Varlee Sanor, Yatta Wapoe, Dash Kwayon, David J Blackley and 13 more

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. COVID-19 and global mental health.The lancet. Psychiatry · 2021
    Article
  6. COVID-19 contact tracing: The Welsh experience.Public health in practice (Oxford, England) · 2020
    Article
  7. The implications of silent transmission for the control of COVID-19 outbreaks.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Caitlin M WolfeEbola Response Team, World Health Organization, Monrovia, Liberia.
Esther L HamblionEbola Response Team, World Health Organization, Monrovia, Liberia.ORCID http://orcid.org/0000-0003-4250-3696
Jacqueline SchulteEbola Response Team, Action contre la Faim, Monrovia, Liberia.
Parker WilliamsEbola Response Team, International Rescue Committee, Monrovia, Liberia.
Augustine KoryonEbola Response Team, International Rescue Committee, Monrovia, Liberia.
Jonathan EndersEbola Response Team, Liberia Ministry of Health, Monrovia, Liberia.
Varlee SanorEbola Response Team, Liberia Ministry of Health, Monrovia, Liberia.
Yatta WapoeEbola Response Team, Liberia Ministry of Health, Monrovia, Liberia.
Dash KwayonEbola Response Team, Liberia Ministry of Health, Monrovia, Liberia.
David J BlackleyEbola Response Team, United States Centers for Disease Control and Prevention, Monrovia, Liberia.
Anthony S LaneyEbola Response Team, United States Centers for Disease Control and Prevention, Monrovia, Liberia.
Emily J WestonEbola Response Team, United States Centers for Disease Control and Prevention, Monrovia, Liberia.
Emily K DokuboEbola Response Team, United States Centers for Disease Control and Prevention, Monrovia, Liberia.
Gloria Davies-WayneEbola Response Team, World Health Organization, Monrovia, Liberia.
Annika WendlandEbola Response Team, World Health Organization, Monrovia, Liberia.
Valerie T S DawEbola Response Team, World Health Organization, Monrovia, Liberia.
Mehboob BadiniEbola Response Team, World Health Organization, Monrovia, Liberia.
Peter ClementEbola Response Team, World Health Organization, Monrovia, Liberia.
Nuha MahmoudEbola Response Team, World Health Organization, Monrovia, Liberia.
Desmond WilliamsEbola Response Team, United States Centers for Disease Control and Prevention, Monrovia, Liberia.
Alex GasasiraEbola Response Team, World Health Organization, Monrovia, Liberia.
Tolbert G NyenswahEbola Response Team, Liberia Ministry of Health, Monrovia, Liberia.
Mosoka FallahEbola Response Team, Liberia Ministry of Health, Monrovia, Liberia.

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundContact tracing is one of the key response activities necessary for halting Ebola Virus Disease (EVD) transmission. Key elements of contact tracing include identification of persons who have been in contact with confirmed EVD cases and careful monitoring for EVD symptoms, but the details of implementation likely influence their effectiveness. In November 2015, several months after a major Ebola outbreak was controlled in Liberia, three members of a family were confirmed positive for EVD in the Duport Road area of Monrovia. The cluster provided an opportunity to implement and evaluate modified approaches to contact tracing.

methodsThe approaches employed for improved contact tracing included classification and risk-based management of identified contacts (including facility based isolation of some high risk contacts, provision of support to persons being monitored, and school-based surveillance for some persons with potential exposure but not listed as contacts), use of phone records to help locate missing contacts, and modifications to data management tools. We recorded details about the implementation of these approaches, report the overall outcomes of the contact tracing efforts and the challenges encountered, and provide recommendations for management of future outbreaks.

results165 contacts were identified (with over 150 identified within 48 hours of confirmation of the EVD cases) and all initially missing contacts were located. Contacts were closely monitored and promptly tested if symptomatic; no contacts developed disease. Encountered challenges related to knowledge gaps among contact tracing staff, data management, and coordination of contact tracing activities with efforts to offer Ebola vaccine.

conclusionsThe Duport Road EVD cluster was promptly controlled. Missing contacts were effectively identified, and identified contacts were effectively monitored and rapidly tested. There is a persistent risk of EVD reemergence in Liberia; the experience controlling each cluster can help inform future Ebola control efforts in Liberia and elsewhere.

Indexed as

AdolescentAdultAgedChildChild, PreschoolContact TracingDisease OutbreaksFemaleHemorrhagic Fever, EbolaHumansInfantInfant, NewbornLiberiaMaleMiddle AgedVaccination

Identifiers

PMID28575034
PMCPMC5470714

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.