ArticlePloS one2017
Childhood chronic conditions and health-related quality of life: Findings from a large population-based study.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 48 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Virtual Acceptance Commitment Therapy (ACT): A Randomized Controlled Trial to Evaluate a Web-Based Intervention for Stress in Adolescents With Chronic Conditions
Turkish Adaptation and Psychometric Evaluation of the Sleep Screening Tool for Children and Adolescents With Complex Chronic Conditions
Who cites it
48 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- A systematic scoping review and gap analysis of questionnaires to assess multimorbidity among children.Pediatric research · 2026Pooled it
- The magnitude of multimorbidity in childhood: a global systematic review.Systematic reviews · 2026Pooled it
- Integrated care for children and young people with special health and care needs: a systematic review.Archives of disease in childhood · 2024Pooled it
- Quality of life in children suffering from headaches: a systematic literature review.The journal of headache and pain · 2023Pooled it
- The Impact of Childhood Attention-Deficit/Hyperactivity Disorder (ADHD) on Children's Health-Related Quality of Life: A Systematic Review and Meta-Analysis.Journal of attention disorders · 2023Pooled it
- Skin care interventions in infants for preventing eczema and food allergy.The Cochrane database of systematic reviews · 2022Pooled it
- The Role of Health Literacy in Health Behavior, Health Service Use, Health Outcomes, and Empowerment in Pediatric Patients with Chronic Disease: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Skin care interventions in infants for preventing eczema and food allergy.The Cochrane database of systematic reviews · 2021Pooled it
- Multidisciplinary lifestyle intervention in children and adolescents - results of the project GRIT (Growth, Resilience, Insights, Thrive) pilot study.BMC pediatrics · 2020Trial
- SKIP (Supporting Kids with diabetes In Physical activity): Feasibility of a randomised controlled trial of a digital intervention for 9-12 year olds with type 1 diabetes mellitus.BMC public health · 2019Trial
- Persistent Food Insecurity and Overweight/Obesity Risk in Offspring of Individuals With Gestational Diabetes.Pediatric obesity · 2026Observational
- Integration of Early Child Development and Care for Hospitalized Small and Sick Children: A Holistic Approach to Pediatric Health.International journal of preventive medicine · 2026Review
- Asthma, Medication Use, and Dental Caries in Adolescents: A Population-Based Study.Caries research · 2026Article
- Health-related quality of life in patients with paediatric inflammatory bowel disease: IMPACT-III validation in Germany.Health and quality of life outcomes · 2025Article
- Feasibility of a group-based intervention to enhance health-related quality of life and physical activity in children and adolescents with chronic illness: a study protocol.Pilot and feasibility studies · 2025Article
- Care needs and factors reducing caregiver burden for children with special health care needs in out-of-home care in Japan: An observational study.Japan journal of nursing science : JJNS · 2025Observational
- Risk and Protective Factors Associated with Increased Burden in Caring for Children: An Observational Study of Japanese General Households.Pediatric reports · 2025Article
- Barriers and Facilitators to Psychological Safety During Medical Procedures Among Individuals Diagnosed with Chronic Illness in Childhood.Healthcare (Basel, Switzerland) · 2025Article
- Associations Between Family Factors and Mental Health Service Use Among Children with Physical Illness: the Mediating Role of Child Psychopathology Trajectories.Child psychiatry and human development · 2025Article
- Impact of asthma control on quality of life among palestinian children.Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study was to assess the impact of health-related quality of life (HRQOL) across prevalent chronic conditions, individually and comorbid, in school-aged children in the Netherlands. 5301 children aged 4-11 years from the Dutch Health Interview Survey were included. Parents completed questionnaires regarding child and parental characteristics. HRQOL of children was measured using the Child Health Questionnaire Parent Form 28 (CHQ-PF28). Independent-t tests were used to assess differences in the mean scores of the CHQ-PF28 summary scales and profile scales between children with a prevalent chronic condition (excluding or including children with multiple chronic conditions) and children without a chronic condition. Cohen's effect sizes (d) were calculated to assess the clinical significance of difference. The mean age of children was 7.55 (SD 2.30) years; 50.0% were boys. In children without any chronic condition, the mean score of physical summary scale (PhS) was 58.53 (SD 4.28) and mean score of the psychosocial summary scale (PsS) was 53.86 (SD 5.87). Generally, PhS and/or PsS scores in children with only one condition were lower (p<0.05) than for children without chronic conditions. When children with multiple conditions were included, mean scores of CHQ-PF28 summary and profile scales were generally lower than when they were excluded. The present study shows important information regarding the impact of prevalent chronic conditions on HRQOL in a representative population-based sample of school-aged children in the Netherlands. The information could be used for developing a more holistic approach to patient care and a surveillance framework for health promotion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.