ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2018
Costamere protein expression and tissue composition of rotator cuff muscle after tendon release in sheep.
Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- Surgical injury and repair of hip external rotators in THA via posterior approach: a three-dimensional MRI-evident quantitative prospective study.BMC musculoskeletal disorders · 2019Trial
- Transcriptional time course after rotator cuff repair in 6 month old female rabbits.Frontiers in physiology · 2023Article
- Spatial transcriptomics tools allow for regional exploration of heterogeneous muscle pathology in the pre-clinical rabbit model of rotator cuff tear.Journal of orthopaedic surgery and research · 2022Article
- Large animal models for the study of tendinopathy.Frontiers in cell and developmental biology · 2022Review
- Animal models for study on rotator cuff injury.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021Article
- Article
- Time course of costamere-related alterations in focal adhesion signaling and composition of rat soleus muscle after achilles tenotomy.Data in brief · 2019Article
- Inhibition of calpain delays early muscle atrophy after rotator cuff tendon release in sheep.Physiological reports · 2018Article
- Knee Extensors Muscle Plasticity Over a 5-Years Rehabilitation Process After Open Knee Surgery.Frontiers in physiology · 2018Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous studies suggested that degradation of contractile tissue requires cleavage of the costamere, a structural protein complex that holds sarcomeres in place. This study examined if costamere turnover is affected by a rotator cuff tear in a previously established ovine model. We found the activity of focal adhesion kinase (FAK), a main regulator of costamere turnover, was unchanged at 2 weeks but decreased by 27% 16 weeks after surgical release of the infraspinatus tendon. This was accompanied by cleavage of the costamere protein talin into a 190 kDa fragment while full length talin remained unchanged. At 2 weeks after tendon release, muscle volume decreased by 17 cm
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