Evidence map›Paper›PMID 28574491›Full record

ArticleEye (London, England)2017

Atrophy of retinal inner layers is associated with poor vision after endophthalmitis: a spectral domain optical coherence tomography study.

X Lu, W Chen, H Xia, K Zheng, C Jin, D S C Ng, H Chen

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Eye (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

X LuJoint Shantou International Eye Center, Shantou University, Chinese University of Hong Kong, Shantou, China.
W ChenJoint Shantou International Eye Center, Shantou University, Chinese University of Hong Kong, Shantou, China.
H XiaJoint Shantou International Eye Center, Shantou University, Chinese University of Hong Kong, Shantou, China.
K ZhengJoint Shantou International Eye Center, Shantou University, Chinese University of Hong Kong, Shantou, China.
C JinJoint Shantou International Eye Center, Shantou University, Chinese University of Hong Kong, Shantou, China.
D S C NgDepartment of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong, China.
H ChenJoint Shantou International Eye Center, Shantou University, Chinese University of Hong Kong, Shantou, China.
Chinese University of Hong Kong · CNShantou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PurposeTo investigate the retinal structural changes in endophthalmitis and their association with visual outcome.Patients and methodsForty-five eyes of 45 patients diagnosed with endophthalmitis were included. Spectral domain optical coherence tomography (SD-OCT) was performed after inflammation was controlled. The relationship between SD-OCT features and best-corrected visual acuity (BCVA) at the last follow-up was analyzed.ResultsThe structural changes included inner segment ellipsoid (ISe) disruption (49%), atrophy of retinal inner layers (24%), epimacular membrane (24%), and macular edema (24%). BCVA was worse in patients with ISe disruption (P=0.005) and retinal inner layers' atrophy (P=0.004) compared with those without. There was no significant difference of BCVA between the patients with and without epimacular membrane, or intraretinal cysts. Multivariate regression showed that atrophy of retinal inner layers (b=0.41±0.17, P=0.022) was the only independent factor associated with BCVA.ConclusionAtrophy of retinal inner layers is associated with visual impairment in endophthalmitis, despite successful management.

Indexed as

Visual AcuityAdolescentAdultAgedAged, 80 and overAtrophyChildChild, PreschoolEndophthalmitisFemaleFluorescein AngiographyFollow-Up StudiesFundus OculiHumansMaleMiddle Aged

Identifiers

PMID28574491
PMCPMC5639185
OpenAlexW2620723191

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.