Evidence map›Paper›PMID 28574475›Full record

ArticleNutrients2017

Feeding a Mixture of Choline Forms to Lactating Dams Improves the Development of the Immune System in Sprague-Dawley Rat Offspring.

Caroline Richard, Erin D Lewis, Susan Goruk, Emily Wadge, Jonathan M Curtis, René L Jacobs, Catherine J Field

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Caroline RichardDepartment of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB T6G 2E1, Canada. cr5@ualberta.ca.
Erin D LewisDepartment of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB T6G 2E1, Canada. Erin.Lewis@tufts.edu.
Susan GorukDepartment of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB T6G 2E1, Canada. sgoruk@ualberta.ca.
Emily WadgeDepartment of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB T6G 2E1, Canada. wadge@ualberta.ca.
Jonathan M CurtisDepartment of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB T6G 2E1, Canada. jcurtis1@ualberta.ca.
René L JacobsDepartment of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB T6G 2E1, Canada. rjacobs@ualberta.ca.
Catherine J FieldDepartment of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB T6G 2E1, Canada. cjfield@ualberta.ca.
University of Alberta · CATufts University · US

Funding

Interaction of Nutrient & Organochlorine AbsorptionR01ES014464 · NIEHS · UNIVERSITY OF CINCINNATI · PI TSO, PATRICK · 2007 to 2010
$1.3M
NIEHS NIH HHS R01 ES014464
6 · The paper itself

Abstract

Dietary choline is essential during lactation, but few studies have examined the implications of feeding a mixture of choline forms on immune function. This study investigates the impact of feeding lactating dams different mixtures of choline forms, similar to those in human diets, on the development and later immune function of suckled offspring. Sprague-Dawley lactating dams (

Indexed as

Maternal Nutritional Physiological PhenomenaAnimalsAnimals, NewbornCholineConcanavalin ADendritic CellsDietFemaleImmune SystemInterferon-gammaInterleukin-10Interleukin-1betaLactationLipopolysaccharidesRatsRats, Sprague-DawleyCholineConcanavalin AInterferon-gammaInterleukin-10Interleukin-1betaLipopolysaccharidesTumor Necrosis Factor-alphacholineglycerophosphocholinegrowthimmunologylactation periodphosphatidylcholinespleenSprague-Dawley rat

Identifiers

PMID28574475
PMCPMC5490546
OpenAlexW2620971443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.