Evidence map›Paper›PMID 28574436›Full record

ArticleInternational journal of molecular sciences2017

Qualitative and Quantitative Assessment of Vascular Changes in Diabetic Macular Edema after Dexamethasone Implant Using Optical Coherence Tomography Angiography.

Lisa Toto, Rossella D'Aloisio, Marta Di Nicola, Giuseppe Di Martino, Silvio Di Staso, Marco Ciancaglini, Daniele Tognetto, Leonardo Mastropasqua

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Application of optical coherence tomography in clinical diagnosis.Journal of X-ray science and technology · 2019
    Pooled it
  4. The Anatomic and Functional Outcomes of Ozurdex-Aided Vitrectomy in Proliferative Diabetic Retinopathy.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Trial
  5. Trial
  6. Review
  7. Article
  8. Article
  9. Factors affecting optical coherence tomography angiography signal strength index in patients receiving intravitreal injection treatment.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
  10. Review
  11. Article
  12. Ophthalmic imaging in diabetic retinopathy: A review.Clinical & experimental ophthalmology · 2022
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Lisa TotoOphthalmology Clinic, Department of Medicine and Science of Ageing, University "G. D'Annunzio" Chieti-Pescara, Chieti 66100, Italy. l.toto@unich.it.
Rossella D'AloisioDepartment of Medicine, Surgery and Health Sciences, University of Trieste, Trieste 34100, Italy. ross.daloisio@gmail.com.
Marta Di NicolaDepartment of Medical, Oral and Biotechnological Sciences, Laboratory of Biostatistics, University "G. D'Annunzio" Chieti-Pescara, Chieti 66100, Italy. mdinicola@unich.it.
Giuseppe Di MartinoSchool of Hygiene and Preventive Medicine, Department of Medicine and Science of Ageing, University "G. D'Annunzio" Chieti-Pescara, Chieti 66100, Italy. peppinodimartino@hotmail.com.
Silvio Di StasoOphthalmology Clinic, Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila 67100, Italy. silvio.distaso@cc.univaq.it.
Marco CiancagliniOphthalmology Clinic, Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila 67100, Italy. marco.ciancaglini@cc.univaq.it.
Daniele TognettoDepartment of Medicine, Surgery and Health Sciences, University of Trieste, Trieste 34100, Italy. tognetto@units.it.
Leonardo MastropasquaOphthalmology Clinic, Department of Medicine and Science of Ageing, University "G. D'Annunzio" Chieti-Pescara, Chieti 66100, Italy. mastropa@unich.it.
University of Chieti-Pescara · ITUniversity of L'Aquila · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate retinal and choriocapillaris vessel changes in diabetic macular edema (DME) after the intravitreal dexamethasone implant (IDI) using optical coherence tomography angiography (OCTA). Moreover, a comparison between morphological and functional parameters of DME and healthy patients was performed. Twenty-five eyes of 25 type 2 diabetic retinopathy patients complicated by macular edema (DME group) and 25 healthy subjects (control group) were enrolled. Superficial capillary plexus density (SCPD) and deep capillary plexus density (DCPD) in the foveal and parafoveal areas, choricapillary density (CCD) and optic disc vessel density (ODVD) were detected using OCTA at baseline and after 7, 30, 60, 90 and 120 days post injection. Best corrected visual acuity (BCVA), retinal sensitivity, and central retinal thickness (CMT) were also evaluated in both groups of patients. A statistically significant difference between the two groups (DME and controls) was found in terms of functional (MP,

Indexed as

AgedAngiographyDexamethasoneDiabetes Mellitus, Type 2Diabetic RetinopathyDrug Delivery SystemsFemaleGlucocorticoidsHumansMacular EdemaMaleMiddle AgedRetinaRetinal VesselsTomography, Optical CoherenceDexamethasoneGlucocorticoidsdiabetic macular edemadiabetic retinopathyintravitreal dexamethasone implantoptical coherence tomography angiography

Identifiers

PMID28574436
PMCPMC5486004
OpenAlexW2620910292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.