Evidence map›Paper›PMID 28574405›Full record

ArticlePhysics in medicine and biology2017

Multi-institutional MicroCT image comparison of image-guided small animal irradiators.

Chris D Johnstone, Patricia Lindsay, Edward E Graves, Eugene Wong, Jessica R Perez, Yannick Poirier, Youssef Ben-Bouchta, Thilakshan Kanesalingam, Haijian Chen, Ashley E Rubinstein and 2 more

Open access · greenAbstract readComparative Study
In one paragraph

Article in Physics in medicine and biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Chris D JohnstoneDepartment of Physics and Astronomy, University of Victoria, Victoria, BC, Canada.
Patricia LindsayRadiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Edward E GravesDepartment of Radiation Oncology, Stanford University, Stanford, CA, United States of America.
Eugene WongDepartment of Physics and Astronomy, University of Western Ontario, London, ON, Canada.
Jessica R PerezMedical Physics Unit, McGill University, Montreal, QC, Canada.
Yannick PoirierDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, United States of America.
Youssef Ben-BouchtaDepartment of Medical Physics, British Columbia Cancer Agency, Vancouver, BC, Canada.
Thilakshan KanesalingamXstrahl Inc., Atlanta, GA, United States of America.
Haijian ChenDepartment of Radiation Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, United States of America.
Ashley E RubinsteinDepartment of Radiation Physics, University of Texas, MD Anderson Cancer Center, Houston, TX, United States of America.ORCID 0000-0003-0221-4603
Ke ShengDepartment of Radiation Oncology, University of California, Los Angeles, CA, United States of America.
Magdalena Bazalova-CarterDepartment of Physics and Astronomy, University of Victoria, Victoria, BC, Canada.
University of Victoria · CA

Funding

Small Animal Radiation Research Platform @ StanfordS10OD018208 · OD · STANFORD UNIVERSITY · PI GRAVES, EDWARD E. · 2014 to 2014
$600k
NIH HHS S10 OD018208
6 · The paper itself

Abstract

To recommend imaging protocols and establish tolerance levels for microCT image quality assurance (QA) performed on conformal image-guided small animal irradiators. A fully automated QA software SAPA (small animal phantom analyzer) for image analysis of the commercial Shelley micro-CT MCTP 610 phantom was developed, in which quantitative analyses of CT number linearity, signal-to-noise ratio (SNR), uniformity and noise, geometric accuracy, spatial resolution by means of modulation transfer function (MTF), and CT contrast were performed. Phantom microCT scans from eleven institutions acquired with four image-guided small animal irradiator units (including the commercial PXi X-RAD SmART and Xstrahl SARRP systems) with varying parameters used for routine small animal imaging were analyzed. Multi-institutional data sets were compared using SAPA, based on which tolerance levels for each QA test were established and imaging protocols for QA were recommended. By analyzing microCT data from 11 institutions, we established image QA tolerance levels for all image quality tests. CT number linearity set to R

Indexed as

AnimalsPhantoms, ImagingSignal-To-Noise RatioX-Ray Microtomography

Identifiers

PMID28574405
PMCPMC5800981
OpenAlexW2620629844

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.