Evidence map›Paper›PMID 28574338›Full record

ArticleeLife2017

Synchronized HIV assembly by tunable PIP

Frauke Mücksch, Vibor Laketa, Barbara Müller, Carsten Schultz, Hans-Georg Kräusslich

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 56 citations in OpenAlex.

  1. Mechanisms of HIV-1 assembly, release and maturation.Nature reviews. Microbiology · 2026
    Review
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  6. Review
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  8. Article
  9. The "basics" of HIV-1 assembly.PLoS pathogens · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Neutral sphingomyelinase 2 is required for HIV-1 maturation.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  14. Inhibition of neutral sphingomyelinase 2 impairs HIV-1 envelope formation and substantially delays or eliminates viral rebound.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  15. Article
  16. Atomic view of the HIV-1 matrix lattice; implications on virus assembly and envelope incorporation.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  17. Review
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  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Frauke MückschDepartment of Infectious Diseases, Virology, University Hospital Heidelberg, Heidelberg, Germany.ORCID 0000-0002-0132-5101
Vibor LaketaDepartment of Infectious Diseases, Virology, University Hospital Heidelberg, Heidelberg, Germany.
Barbara MüllerDepartment of Infectious Diseases, Virology, University Hospital Heidelberg, Heidelberg, Germany.ORCID 0000-0001-5726-5585
Carsten SchultzCell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Hans-Georg KräusslichDepartment of Infectious Diseases, Virology, University Hospital Heidelberg, Heidelberg, Germany.ORCID 0000-0002-8756-329X
Heidelberg University · DEOregon Health & Science University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HIV-1 assembles at the plasma membrane (PM) of infected cells. PM association of the main structural protein Gag depends on its myristoylated MA domain and PM PI(4,5)P

Indexed as

Virus AssemblyCell LineCell Membranegag Gene Products, Human Immunodeficiency VirusHIV-1HumansPhosphatidylinositol 4,5-Diphosphategag Gene Products, Human Immunodeficiency VirusPhosphatidylinositol 4,5-Diphosphateassemblycell biologychemical dimerizerGagHuman Immunodeficiency Virusinfectious diseasemicrobiologyPI(4,5)P2virus

Identifiers

PMID28574338
PMCPMC5495570
OpenAlexW2620843714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.