Evidence map›Paper›PMID 28574057›Full record

ReviewCancer gene therapy2017

New methods in the diagnosis of cancer and gene therapy of cancer based on nanoparticles.

M A Zaimy, N Saffarzadeh, A Mohammadi, H Pourghadamyari, P Izadi, A Sarli, L K Moghaddam, S R Paschepari, H Azizi, S Torkamandi and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cancer gene therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
119citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

119 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Advances in carrier-free nanodrug delivery systems.Drug delivery and translational research · 2026
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59 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

M A ZaimyDepartment of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
N SaffarzadehDepartment of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
A MohammadiCenter of Excellence for Biodiversity, Faculty of Natural Science, University of Tabriz, Tabriz, Iran.
H PourghadamyariDepartment of Biochemistry, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
P IzadiDepartment of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
A SarliDepartment of Medical Genetics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
L K MoghaddamDepartment of Developmental Cell Biology, School of Biological Sciences, Azad University, Tehran North Branch, Tehran, Iran.
S R PaschepariDepartment of Developmental Cell Biology, School of Biological Sciences, Azad University, Tehran North Branch, Tehran, Iran.
H AziziDepartment of Medical Parasitology, Zabol University of Medical Sciences, Zabol, Iran.
S TorkamandiDepartment of Medical Genetics and immunology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
J Tavakkoly-BazzazDepartment of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is one of the leading cause of death in the world with the prevalence of >10 million mortalities annually. Current cancer treatments include surgical intervention, radiation, and taking chemotherapeutic drugs, which often kill the healthy cells and result in toxicity in patients. Therefore, researchers are looking for ways to be able to eliminate just cancerous cells. Intra-tumor heterogeneity of cancerous cells is the main obstacle on the way of an effective cancer treatment. However, better comprehension of molecular basis of tumor and the advent of new diagnostic technologies can help to improve the treatment of various cancers. Therefore, study of epigenetic changes, gene expression of cancerous cells and employing methods that enable us to correct or minimize these changes is critically important. In this paper, we will review the recent advanced strategies being used in the field of cancer research.

Indexed as

Genetic TherapyNeoplasmsHumansNanoparticles

Identifiers

PMID28574057

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.