Evidence map›Paper›PMID 28573592›Full record

ReviewMethods in molecular biology (Clifton, N.J.)2017

Protein Data Bank (PDB): The Single Global Macromolecular Structure Archive.

Stephen K Burley, Helen M Berman, Gerard J Kleywegt, John L Markley, Haruki Nakamura, Sameer Velankar

Abstract readReview
In one paragraph

Review in Methods in molecular biology (Clifton, N.J.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 571 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
571citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

571 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Review
  8. APDB: A Large-Scale Repository of Predicted 2D and 3D Aptamer Structures.Journal of chemical information and modeling · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Agonist-specific conformational dynamics at the βBritish journal of pharmacology · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Stoic: fast and accurate protein stoichiometry prediction.Bioinformatics (Oxford, England) · 2026
    Article

511 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Stephen K BurleyResearch Collaboratory for Structural Bioinformatics Protein Data Bank, Center for Integrative Proteomics, Research, Institute for Quantitative Biomedicine, and Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ, 08854, USA. stephen.burley@rcsb.org.
Helen M BermanResearch Collaboratory for Structural Bioinformatics Protein Data Bank, Center for Integrative Proteomics, Research, Institute for Quantitative Biomedicine, and Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ, 08854, USA.
Gerard J KleywegtProtein Data Bank in Europe, European Molecular Biology Laboratory-European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, CB10 1SD, UK.
John L MarkleyBioMagResBank, Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Haruki NakamuraProtein Data Bank Japan, Institute for Protein Research, Osaka University, Suita, Osaka, 565-0871, Japan.
Sameer VelankarProtein Data Bank in Europe, European Molecular Biology Laboratory-European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, CB10 1SD, UK.

Funding

The BMRB as an evolving resource for biomolecular structure-function researchR01GM109046 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI HOCH, JEFFREY C · 2014 to 2022
$6.6M
Biotechnology and Biological Sciences Research CouncilMedical Research CouncilNIGMS NIH HHS R01 GM109046Wellcome Trust
6 · The paper itself

Abstract

The Protein Data Bank (PDB)--the single global repository of experimentally determined 3D structures of biological macromolecules and their complexes--was established in 1971, becoming the first open-access digital resource in the biological sciences. The PDB archive currently houses ~130,000 entries (May 2017). It is managed by the Worldwide Protein Data Bank organization (wwPDB; wwpdb.org), which includes the RCSB Protein Data Bank (RCSB PDB; rcsb.org), the Protein Data Bank Japan (PDBj; pdbj.org), the Protein Data Bank in Europe (PDBe; pdbe.org), and BioMagResBank (BMRB; www.bmrb.wisc.edu). The four wwPDB partners operate a unified global software system that enforces community-agreed data standards and supports data Deposition, Biocuration, and Validation of ~11,000 new PDB entries annually (deposit.wwpdb.org). The RCSB PDB currently acts as the archive keeper, ensuring disaster recovery of PDB data and coordinating weekly updates. wwPDB partners disseminate the same archival data from multiple FTP sites, while operating complementary websites that provide their own views of PDB data with selected value-added information and links to related data resources. At present, the PDB archives experimental data, associated metadata, and 3D-atomic level structural models derived from three well-established methods: crystallography, nuclear magnetic resonance spectroscopy (NMR), and electron microscopy (3DEM). wwPDB partners are working closely with experts in related experimental areas (small-angle scattering, chemical cross-linking/mass spectrometry, Forster energy resonance transfer or FRET, etc.) to establish a federation of data resources that will support sustainable archiving and validation of 3D structural models and experimental data derived from integrative or hybrid methods.

Indexed as

Crystallography, X-RayDatabases, ProteinHumansInternational CooperationMacromolecular SubstancesMicroscopy, ElectronModels, MolecularNuclear Magnetic Resonance, BiomolecularProtein ConformationProteinsStereoisomerismMacromolecular SubstancesProteins3D electron microscopyChemical Component DictionaryCrystallographyIntegrative or hybrid methodsNEFNMR Exchange FormatNMR spectroscopyNMR-STARPDBPDBx/mmCIFProtein Data BankWorldwide Protein Data BankwwPDB

Identifiers

PMID28573592
PMCPMC5823500

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.