Evidence map›Paper›PMID 28573538›Full record

ArticleHeart and vessels2017

Nutritional screening based on the controlling nutritional status (CONUT) score at the time of admission is useful for long-term prognostic prediction in patients with heart failure requiring hospitalization.

Isao Nishi, Yoshihiro Seo, Yoshie Hamada-Harimura, Kimi Sato, Seika Sai, Masayoshi Yamamoto, Tomoko Ishizu, Akinori Sugano, Kenichi Obara, Longmei Wu and 4 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Heart and vessels, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Association of controlling nutritional status score and long-term mortality in acute pulmonary embolism.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2025
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  10. Controlling Nutritional Status Score Predicts In-Hospital Mortality in Acute Pulmonary Embolism.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Isao NishiDepartment of Cardiology, Tsuchiura Clinical Education and Training Center, University of Tsukuba Hospital, Tsuchiura, Japan. isanishi-circ@kasumi-hosp.jp.
Yoshihiro SeoCardiovascular Division, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Yoshie Hamada-HarimuraCardiovascular Division, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Kimi SatoCardiovascular Division, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Seika SaiDepartment of Cardiology, Hitachi, Ltd., Hitachinaka General Hospital, Hitachinaka, Japan.
Masayoshi YamamotoCardiovascular Division, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Tomoko IshizuDepartment of Clinical Laboratory Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Akinori SuganoDivision of Cardiology, Ryugasaki Saiseikai General Hospital, Ryugasaki, Japan.
Kenichi ObaraDivision of Cardiology, Ryugasaki Saiseikai General Hospital, Ryugasaki, Japan.
Longmei WuDepartment of Cardiology, National Hospital Organization Kasumigaura Medical Center, 2-7-14 Shimotakatsu, Tsuchiura, Ibaraki, 300-8585, Japan.
Shoji SuzukiDepartment of Cardiology, National Hospital Organization Kasumigaura Medical Center, 2-7-14 Shimotakatsu, Tsuchiura, Ibaraki, 300-8585, Japan.
Akira KoikeMedical Science, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Kazutaka AonumaCardiovascular Division, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Ibaraki Cardiovascular Assessment Study-Heart Failure Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of the study was to clarify whether controlling nutritional status (CONUT) is useful for predicting the long-term prognosis of patients hospitalized with heart failure (HF). A total of 482 (57.5%) HF patients from the Ibaraki Cardiovascular Assessment Study-HF (N = 838) were enrolled (298 men, 71.7 ± 13.6 years). At admission, blood samples were collected and nutritional status assessed using CONUT. CONUT scores were defined as follows: 0-1, normal; 2-4, light; 5-8, moderate; and 9-12, severe undernutrition. Accordingly, 352 (73%) patients had light-to-severe nutritional disturbances. In the follow-up period [median 541.5 (range 354-786) days], 109 deaths were observed. A Kaplan-Meier analysis revealed that all-cause deaths occurred more frequently in HF patients with nutritional disturbances [n = 93 (26.4%)] than in those with normal nutrition [n = 16 (12.3%); log-rank p < 0.001]. The Cox proportional hazard analyses revealed that a per point increase in the CONUT score was associated with an increased risk of all-cause death (hazard ratio 1.142; 95% confidence interval, 1.044-1.249) after controlling simultaneously for age, sex, previous history of HF hospitalization, log brain natriuretic peptide, and use of therapeutic agents at admission (tolvaptan and aldosterone antagonists). This study suggests that nutritional screening using CONUT scores is helpful in predicting the long-term prognosis of patients hospitalized with HF in a multicenter registry setting.

Indexed as

Nutritional StatusNutrition AssessmentAgedCause of DeathFemaleHeart FailureHospitalizationHumansKaplan-Meier EstimateMalePrognosisRisk FactorsSurvival RateTime FactorsCONUT scoreHeart failureNutritional screeningPrognosis

Identifiers

PMID28573538

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.