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ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2017

Patient-reported symptoms during radiotherapy : Clinically relevant symptom burden in patients treated with palliative and curative intent.

Philipp Körner, Katja Ehrmann, Johann Hartmannsgruber, Michaela Metz, Sabrina Steigerwald, Michael Flentje, Birgitt van Oorschot

Registry-linked trialAbstract read
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In one paragraph

Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04069494 (Descriptors and Predictors of Burden and Information Needs on Symptom Self-management in Thai Patients With Lung Cancer and Their Family Caregivers During Palliative Radiotherapy), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04069494 completednot on this mapstarted 2019, after this paper: background citation

Descriptors and Predictors of Burden and Information Needs on Symptom Self-management in Thai Patients With Lung Cancer and Their Family Caregivers During Palliative Radiotherapy

Typeobservational_patient_registrySponsorChulabhorn Cancer CenterRan2019 to 2020Enrolled112ConditionsAdvanced Lung Cancer, SymptomsArmsquestionnaires
3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Bridging gaps in care: medical student home visits and their influence on radiation oncology patients.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
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  5. Physical and nonphysical effects of weekly music therapy intervention on the condition of radiooncology patients.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
    Article
  6. Palliative care on the radiation oncology ward-improvements in clinical care through interdisciplinary ward rounds.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
    Article
  7. Article
  8. Article
  9. Age-dependent hemato- and nephrotoxicity in patients with head and neck cancer receiving chemoradiotherapy with weekly cisplatin.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2020
    Article
  10. Article
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  12. Article
  13. Treatment of malnutrition decreases complication rates and shortens the length of hospital stays in a radiation oncology department.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2018
    Article
  14. Predictors of outpatients' request for palliative care service at a medical oncology clinic of a German comprehensive cancer center.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Article
  15. Article
  16. Patient-reported symptoms before palliative radiotherapy predict survival differences.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2018
    Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Philipp KörnerInterdisziplinäres Zentrum Palliativmedizin, Universitätsklinikum Würzburg, Josef-Schneider-Str. 2, 97080, Würzburg, Germany. philipp.koerner@zzm.uzh.ch.ORCID http://orcid.org/0000-0002-9254-7112
Katja EhrmannMedizinische Psychologie und Psychotherapie, Medizinische Soziologie und Rehabilitationswissenschaften, Universitätsklinikum Würzburg, Würzburg, Germany.
Johann HartmannsgruberKinderzahnheilkunde, Praxis Landshut, Landshut, Germany.
Michaela MetzKlinik und Poliklinik für Strahlentherapie, Universitätsklinikum Würzburg, Würzburg, Germany.
Sabrina SteigerwaldKlinik und Poliklinik für Strahlentherapie, Universitätsklinikum Würzburg, Würzburg, Germany.
Michael FlentjeKlinik und Poliklinik für Strahlentherapie, Universitätsklinikum Würzburg, Würzburg, Germany.
Birgitt van OorschotInterdisziplinäres Zentrum Palliativmedizin, Universitätsklinikum Würzburg, Josef-Schneider-Str. 2, 97080, Würzburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe benefits of patient-reported symptom assessment combined with integrated palliative care are well documented. This study assessed the symptom burden of palliative and curative-intent radiation oncology patients. PATIENTS AND

methodsPrior to first consultation and at the end of RT, all adult cancer patients planned to receive fractionated percutaneous radiotherapy (RT) were asked to answer the Edmonton Symptom Assessment Scale (ESAS; nine symptoms from 0 = no symptoms to 10 = worst possible symptoms). Mean values were used for curative vs. palliative and pre-post comparisons, and the clinical relevance was evaluated (symptom values ≥ 4).

resultsOf 163 participating patients, 151 patients (90.9%) completed both surveys (116 curative and 35 palliative patients). Before beginning RT, 88.6% of palliative and 72.3% of curative patients showed at least one clinically relevant symptom. Curative patients most frequently named decreased general wellbeing (38.6%), followed by tiredness (35.0%), anxiety (32.4%), depression (30.0%), pain (26.3%), lack of appetite (23.5%), dyspnea (17.8%), drowsiness (8.0%) and nausea (6.1%). Palliative patients most frequently named decreased general wellbeing (62.8%), followed by pain (62.8%), tiredness (60.0%), lack of appetite (40.0%), anxiety (38.0%), depression (33.3%), dyspnea (28.5%), drowsiness (25.7%) and nausea (14.2%). At the end of RT, the proportion of curative and palliative patients with a clinically relevant symptom had increased significantly to 79.8 and 91.4%, respectively; whereas the proportion of patients reporting clinically relevant pain had decreased significantly (42.8 vs. 62.8%, respectively). Palliative patients had significantly increased tiredness. Curative patients reported significant increases in pain, tiredness, nausea, drowsiness, lack of appetite and restrictions in general wellbeing.

conclusionAssessment of patient-reported symptoms was successfully realized in radiation oncology routine. Overall, both groups showed a high symptom burden. The results prove the need of systematic symptom assessment and programs for early integrated supportive and palliative care in radiation oncology.

Indexed as

Dose Fractionation, RadiationHealth StatusPalliative CareQuality of LifeSelf ReportAdolescentAdultAgedAged, 80 and overBone NeoplasmsFatigueFemaleFollow-Up StudiesHumansMaleMiddle AgedPainPalliative careQuality of lifeRadiation oncologyScreening

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.