Evidence map›Paper›PMID 28573223›Full record

ArticleAfrican journal of traditional, complementary, and alternative medicines : AJTCAM2017

CARDIOPROTECTIVE ROLES OF THE CHINESE MEDICINAL FORMULA BAO-XIN-TANG ON ACUTE MYOCARDIAL INFARCTION IN RATS.

Yang Wang, Weihao Wang, Weijun Peng, Weiping Liu, Weijun Cai, Zian Xia, Honggeng Zhang, And Zhihua Xing

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in African journal of traditional, complementary, and alternative medicines : AJTCAM, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Herbal Extract fromLife (Basel, Switzerland) · 2021
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yang WangInstitute of Integrated Medicine, Xiangya Hospital, Central South University, Changsha 410008, P.R. China.
Weihao WangInstitute of Integrated Medicine, Xiangya Hospital, Central South University, Changsha 410008, P.R. China.
Weijun PengDepartment of Integrated Chinese and Western Medicine, The Second Xiangya Hospital, Central South University, Changsha 410011, P.R. China.
Weiping LiuInstitute of Integrated Medicine, Xiangya Hospital, Central South University, Changsha 410008, P.R. China.
Weijun CaiDepartment of Histology & Embryology, School of Basic Medical Sciences, Central South University, Changsha 410013, P.R. China.
Zian XiaInstitute of Integrated Medicine, Xiangya Hospital, Central South University, Changsha 410008, P.R. China.
Honggeng ZhangThe Second People's Hospital of Hunan Province, Changsha 410007, P.R. China.
And Zhihua XingInstitute of Integrated Medicine, Xiangya Hospital, Central South University, Changsha 410008, P.R. China.
Central South University · CNSecond People Hospital of Hunan · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBao-Xin-Tang (BXT) is a traditional Chinese medicinal formula used for the treatment of coronary heart disease and known to have favorable therapeutic benefits. The current study was designed to determine whether BXT has a cardioprotective role for acute myocardial infarction. The underlying mechanisms were also explored. MATERIALS AND

methodsThe Sprague-Dawley rat model of acute myocardial infarction was established by occluding the left anterior descending branch of the coronary artery. After a 3-h ischemic period, we determined the myocardial infarction size, inflammatory components, and antioxidant activities.

resultsThe data showed that BXT could reduce the infarction size and lower the levels of C-reactive protein, interleukin-6, and myeloperoxidase, and increase the activities of superoxide dismutase and the anti-inflammatory cytokine, interleukin-10. These results indicate that administration of BXT, following acute myocardial infarction, could reduce infarct size.

conclusionThe effects of BXT may be related to its anti-inflammatory and anti-oxidative properties.

Indexed as

PhytotherapyAcute DiseaseAnimalsAnti-Inflammatory AgentsAntioxidantsCardiotonic AgentsCoronary VesselsC-Reactive ProteinDrugs, Chinese HerbalInfarctionInflammationInterleukin-10Interleukin-6MaleMyocardial InfarctionMyocardiumAnti-Inflammatory AgentsAntioxidantsCardiotonic AgentsC-Reactive ProteinDrugs, Chinese HerbalInterleukin-10Interleukin-6PeroxidaseSuperoxide Dismutaseanti-inflammatoryanti-oxidativeBao-Xin-Tangcardioprotectiveinfarction size

Identifiers

PMID28573223
PMCPMC5446467
OpenAlexW2576895495

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.