Evidence map›Paper›PMID 28573106›Full record

ArticleFrontiers in oncology2017

No Functional Role for microRNA-342 in a Mouse Model of Pancreatic Acinar Carcinoma.

James Dooley, Vasiliki Lagou, Emanuela Pasciuto, Michelle A Linterman, Haydn M Prosser, Uwe Himmelreich, Adrian Liston

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
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  5. Article
  6. Serum miR-342-3p is a novel diagnostic and prognostic biomarker for non-small cell lung cancer.International journal of clinical and experimental pathology · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

James DooleyTranslational Immunology Laboratory, VIB, Leuven, Belgium.
Vasiliki LagouTranslational Immunology Laboratory, VIB, Leuven, Belgium.
Emanuela PasciutoTranslational Immunology Laboratory, VIB, Leuven, Belgium.
Michelle A LintermanLaboratory of Lymphocyte Signaling and Development, Babraham Institute, Cambridge, UK.
Haydn M ProsserWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK.
Uwe HimmelreichDepartment of Imaging and Pathology, KU Leuven - University of Leuven, Leuven, Belgium.
Adrian ListonTranslational Immunology Laboratory, VIB, Leuven, Belgium.
KU Leuven · BEBabraham Institute · GBWellcome Sanger Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intronic microRNA (miR)-342 has been proposed as a potent tumor-suppressor gene. miR-342 is found to be downregulated or epigenetically silenced in multiple different tumor sites, and this loss of expression permits the upregulation of several key oncogenic pathways. In several different cell lines, lower miR-342 expression results in enhanced proliferation and metastasis potential, both

Indexed as

acinar carcinomain vivomicroRNAsmiR-342-5ppancreatic cancer

Identifiers

PMID28573106
PMCPMC5435746
OpenAlexW2615292139

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.