ArticleThe journal of venomous animals and toxins including tropical diseases2017
Ergosterol isolated from the basidiomycete
Article in The journal of venomous animals and toxins including tropical diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 39 citations in OpenAlex.
- Multitarget Therapeutic Strategies for Chagas Disease: Natural Compounds, Antimicrobial Peptides, and Cell-Based Immunomodulation.Infectious disease reports · 2026Review
- Antibacterial Activity of Extract, Fractions, and Compounds fromPharmaceuticals (Basel, Switzerland) · 2026Article
- Chemical Constituents of Taxodium mucronatum (Cupressaceae) and Some of Its Endophytic Fungi, and Their In Silico and In Vitro Evaluations as SARS-CoV-2 Inhibitors and as Cytotoxic Agents.Chemistry & biodiversity · 2026Article
- In vitro and in silico approaches manifest the anti-leishmanial activity of wild edible mushroomIn silico pharmacology · 2025Article
- Article
- Antimicrobial activities of metabolites isolated from endophytic Aspergillus flavus of Sarcophyton ehrenbergi supported by in-silico study and NMR spectroscopy.Fungal biology and biotechnology · 2023Article
- Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible Mushrooms.Foods (Basel, Switzerland) · 2023Review
- Enyne acetogenins from Porcelia macrocarpa displayed anti-Trypanosoma cruzi activity and cause a reduction in the intracellular calcium level.Scientific reports · 2023Article
- Chemical Defence by Sterols in the Freshwater CiliateBiology · 2022Article
- Antioxidant and Anti-Inflammatory Activity of Five Medicinal Mushrooms of the GenusAntioxidants (Basel, Switzerland) · 2022Article
- Triterpenes fromJournal of natural products · 2022Review
- Alterations in Mycelial Morphology and Flow Cytometry Assessment of Membrane Integrity ofBiology · 2021Article
- Insights into Ergosterol Peroxide's Trypanocidal Activity.Biomolecules · 2019Article
- Bioactive secondary metabolites from new endophytic fungus Curvularia. sp isolated from Rauwolfia macrophylla.PloS one · 2019Article
- Second-generation pterocarpanquinones: synthesis and antileishmanial activity.The journal of venomous animals and toxins including tropical diseases · 2018Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMajor drawbacks of the available treatment against Chagas disease (American trypanosomiasis) include its toxicity and therapeutic inefficiency in the chronic phase of the infection, which makes it a concern among neglected diseases. Therefore, the discovery of alternative drugs for treating chronic Chagas disease requires immediate action. In this work, we evaluated the mushroom
methodsFruit bodies of the basidiomycete
resultsThe most abundant fraction showing the antiparasitic activity was isolated and chemically elucidated, confirming the presence of ergosterol. It showed anti-
conclusionsThe selection of naturally antiparasitic secondary metabolites in basidiomycetes, such as ergosterol, may provide potential scaffolds for drug design studies against neglected diseases.
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