ReviewFrontiers in endocrinology2017
Hunger and Satiety Gauge Reward Sensitivity.
Review in Frontiers in endocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed.
- Enhancing Motivation to Reduce Restrictive Eating: A Novel Approach.The International journal of eating disorders · 2025Trial
- Meal-Induced Symptoms in Children with Dyspepsia-Relationships to Sex and the Presence of Gastroparesis.The Journal of pediatrics · 2021Trial
- Effects of prenatal methadone and buprenorphine exposure on motivated responding for sucrose and gene expression in adult male and female rats.Addiction neuroscience · 2026Article
- Sex-Dependent Effects of Glutamatergic Disruption on Dopaminergic Neuron Subtype Vulnerable in Parkinson's Disease.bioRxiv : the preprint server for biology · 2026Article
- Children's satiety responsiveness moderates the association between food reinforcement and eating in the absence of hunger.Physiology & behavior · 2025Article
- Striatal signaling tracks naturalistic short-term fluctuations in hunger-satiety.bioRxiv : the preprint server for biology · 2025Article
- Article
- Beyond BMI: the complex interplay of reward sensitivity, eating behaviors, and BMI in female college students.Frontiers in psychology · 2025Article
- Improving Food-Related Inhibitory Control Through an mHealth Intervention-A Secondary Outcome Analysis of an RCT.Obesity science & practice · 2024Article
- Article
- Microbiota-gut-brain axis in binge-eating disorder: Towards microbiome-based therapies.Neuroscience applied · 2024Review
- Effort cost of harvest affects decisions and movement vigor of marmosets during foraging.eLife · 2023Article
- Transcranial Magnetic Stimulation for Reducing the Relative Reinforcing Value of Food in Adult Patients With Obesity Pursuing Metabolic and Bariatric Surgery: Protocol for a Pilot, Within-Participants, Sham-Controlled Trial.JMIR research protocols · 2023Article
- Increased intrinsic and synaptic excitability of hypothalamic POMC neurons underlies chronic stress-induced behavioral deficits.Molecular psychiatry · 2023Article
- A common modular design of nervous systems originating in soft-bodied invertebrates.Frontiers in physiology · 2023Article
- Satiety Associated with Calorie Restriction and Time-Restricted Feeding: Central Neuroendocrine Integration.Advances in nutrition (Bethesda, Md.) · 2022Review
- Neurobeachin, a promising target for use in the treatment of alcohol use disorder.Addiction biology · 2022Article
- Hypothalamic effective connectivity at rest is associated with body weight and energy homeostasis.Network neuroscience (Cambridge, Mass.) · 2022Article
- Neural network modelling reveals changes in directional connectivity between cortical and hypothalamic regions with increased BMI.International journal of obesity (2005) · 2021Article
- Food reinforcement and habituation to food are processes related to initiation and cessation of eating.Physiology & behavior · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Many of the neurocircuits and hormones known to underlie the sensations of hunger and satiety also substantially alter the activity of the dopaminergic reward system. Much interest lies in the ways that hunger, satiety, and reward tie together, as the epidemic of obesity seems tied to the recent development and mass availability of highly palatable foods. In this review, we will first discuss the basic neurocircuitry of the midbrain and basal forebrain reward system. We will elaborate how several important mediators of hunger-the agouti-related protein neurons of the arcuate nucleus, the lateral hypothalamic nucleus, and ghrelin-enhance the sensitivity of the dopaminergic reward system. Then, we will elaborate how mediators of satiety-the nucleus tractus solitarius, pro-opiomelanocortin neurons of the arcuate nucleus, and its peripheral hormonal influences such as leptin-reduce the reward system sensitivity. We hope to provide a template by which future research may identify the ways in which highly rewarding foods bypass this balanced system to produce excessive food consumption.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.