Evidence map›Paper›PMID 28572727›Full record

ArticleInternational journal of nanomedicine2017

Organic effects of associating paclitaxel with a lipid-based nanoparticle system on a nonhuman primate,

Danielle Cristinne Azevedo Feio, Nayara Cristina Lima de Oliveira, Edmundo Luis Rodrigues Pereira, Aleksandra Tiemi Morikawa, José Augusto Pereira Carneiro Muniz, Raquel Carvalho Montenegro, Ana Paula Negreiros Nunes Alves, Patrícia Danielle Lima de Lima, Raul Cavalcante Maranhão, Rommel Rodríguez Burbano

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Danielle Cristinne Azevedo FeioHuman Cytogenetics Laboratory, Institute of Biological Sciences, Federal University of Pará, Belem.
Nayara Cristina Lima de OliveiraHuman Cytogenetics Laboratory, Institute of Biological Sciences, Federal University of Pará, Belem.
Edmundo Luis Rodrigues PereiraHuman Cytogenetics Laboratory, Institute of Biological Sciences, Federal University of Pará, Belem.
Aleksandra Tiemi MorikawaHeart Institute, University of Sao Paulo Medical School Hospital, Sao Paulo.
José Augusto Pereira Carneiro MunizEvandro Chagas Institute, Primate National Center, Ananindeua.
Raquel Carvalho MontenegroHuman Cytogenetics Laboratory, Institute of Biological Sciences, Federal University of Pará, Belem.
Ana Paula Negreiros Nunes AlvesDepartment of Clinical Dentistry, Health Sciences Center, Federal University of Ceará, Fortaleza.
Patrícia Danielle Lima de LimaMolecular Biology Laboratory, Post Graduate Program of Amazon Parasitic Biology, Biological and Health Sciences Center, State University of Pará, Belem, Brazil.
Raul Cavalcante MaranhãoHeart Institute, University of Sao Paulo Medical School Hospital, Sao Paulo.
Rommel Rodríguez BurbanoHuman Cytogenetics Laboratory, Institute of Biological Sciences, Federal University of Pará, Belem.
Instituto Federal de Educação, Ciência e Tecnologia do Pará · BRUniversidade de São Paulo · BRUniversidade Federal do Pará · BRInstituto Evandro Chagas · BRUniversidade Federal do Ceará · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipid-based nanoparticle systems have been used as vehicles for chemotherapeutic agents in experimental cancer treatments. Those systems have generally been credited with attenuating the severe toxicity of chemotherapeutic agents. This study aimed to investigate the effects of associating paclitaxel (PTX) with a lipid-based nanoparticle system on a nonhuman primate,

Indexed as

AnimalsAntineoplastic AgentsCebusCholesterolDose-Response Relationship, DrugDrug CarriersEmulsionsLipidsMaleNanoparticlesNeoplasmsPaclitaxelTissue DistributionToxicity Tests, ChronicAntineoplastic AgentsCholesterolDrug CarriersEmulsionsLipidsPaclitaxelCebus apellaLDEnanoparticlespaclitaxeltoxicity

Identifiers

PMID28572727
PMCPMC5441669
OpenAlexW2614619297

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.