Evidence map›Paper›PMID 28572698›Full record

ArticleDisease markers2017

Phosphorylation of Histone H2A.X in Peripheral Blood Mononuclear Cells May Be a Useful Marker for Monitoring Cardiometabolic Risk in Nondiabetic Individuals.

So Ra Yoon, Juhyun Song, Jong Hwa Lee, Oh Yoen Kim

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Disease markers, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

So Ra YoonDepartment of Food Science and Nutrition, Brain Busan 21 Project, Dong-A University, Busan 49315, Republic of Korea.
Juhyun SongDepartment of Biomedical Sciences, Center for Creative Biomedical Scientists, Chonnam National University, Gwangju 61469, Republic of Korea.
Jong Hwa LeeDepartment of Rehabilitation Medicine, Dong-A University Hospital, Busan 49315, Republic of Korea.
Oh Yoen KimDepartment of Food Science and Nutrition, Brain Busan 21 Project, Dong-A University, Busan 49315, Republic of Korea.ORCID 0000-0001-9262-3309
Dong-A University · KRChonnam National University · KRDong-A University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phosphorylation of H2A.X (serine 139) in the histone H2A family located in the downstream of the DNA damage kinase signaling cascade is an important indicator of DNA damage. Recently, phosphorylation of H2A.X was proposed as a sensitive biomarker of aging. This study investigated if phosphorylation of H2A.X in peripheral blood mononuclear cells (PBMCs) is associated with cardiometabolic risk in nondiabetic individuals. Basic parameters and oxidative stress/inflammatory markers were measured in nondiabetic healthy Koreans (

Indexed as

Protein Processing, Post-TranslationalAdultBiomarkersBlood PressureCholesterol, LDLFemaleHistonesHumansMaleMetabolic SyndromeMiddle AgedMonocytesPhosphorylationWaist CircumferenceBiomarkersCholesterol, LDLH2AX protein, humanHistones

Identifiers

PMID28572698
PMCPMC5441116
OpenAlexW2613276649

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.