ArticleScientific reports2017
Transcriptome responses of Lactobacillus acetotolerans F28 to a short and long term ethanol stress.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 49 citations in OpenAlex.
- Investigation on Patulin biotransformation in Zebrafish and its toxicological function evaluation.Mycotoxin research · 2026Article
- Diversity and evolutionary dynamics of universal stress proteins in the Liquorilactobacillus genus.World journal of microbiology & biotechnology · 2026Article
- Ethanolphilic lactic acid bacteriumApplied and environmental microbiology · 2025Article
- Ecological factors that drive microbial communities in culturally diverse fermented foods.BMC microbiology · 2025Article
- Yellow serofluid-inclusion enhanced anaerobic preservation of whole plant maize for subsequently reducing potential methane emission during in vitro ruminal fermentation.BMC microbiology · 2025Article
- Metagenomic insights into microbial community succession and its functional changes during the stage of acetic acid fermentation of shanxi aged vinegar.BMC microbiology · 2025Article
- Effect of Fortified Inoculation with IndigenousFoods (Basel, Switzerland) · 2023Article
- Article
- Probiotic properties and proteomics analysis of ethanol-induced Lactococcus lactis subsp. lactis IL1403.World journal of microbiology & biotechnology · 2023Article
- Revealing potential functions of hypothetical proteins induced by genistein in the symbiosis island of Bradyrhizobium japonicum commercial strain SEMIA 5079 (= CPAC 15).BMC microbiology · 2022Article
- Transcriptome analysis of Lactobacillus rhamnosus GG strain treated with prebiotic - bovine lactoferrin under a cold environment.Journal of food and drug analysis · 2021Article
- Composition and Metabolic Functions of the Microbiome in Fermented Grain during Light-FlavorMicroorganisms · 2020Article
- Ste20 is crucial for dimorphic switching of sporothrix schenckii and affects its global transcriptome.International journal of clinical and experimental pathology · 2020Article
- Transcriptional Regulator AcrR Increases Ethanol Tolerance through Regulation of Fatty Acid Synthesis inApplied and environmental microbiology · 2019Article
- Construction of Synthetic Microbiota for Reproducible Flavor Compound Metabolism in Chinese Light-Aroma-Type Liquor Produced by Solid-State Fermentation.Applied and environmental microbiology · 2019Article
- Bacillus megaterium adapts to acid stress condition through a network of genes: Insight from a genome-wide transcriptome analysis.Scientific reports · 2018Article
- Dynamic microbial succession of Shanxi aged vinegar and its correlation with flavor metabolites during different stages of acetic acid fermentation.Scientific reports · 2018Article
- Effect of the environment microbiota on the flavour of light-flavour Baijiu during spontaneous fermentation.Scientific reports · 2018Article
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lactobacillus acetotolerans is a major microbe contributing to the Chinese liquor fermentation with unknown function. It can be grown well in a high concentration of ethanol. RNA sequencing (RNA-seq) was performed on L. acetotolerans F28 growing in 12% ethanol to determine important genetic mechanisms for both a short and long term adaption to this environment. A genome-wide transcriptional analysis revealed that the most important genetic elements for L. acetotolerans F28 grown in ethanol are related to high levels of stress response and fatty acid biosynthesis, and a reduction of amino acid transport and metabolism after both a short and long time stress. The fatty acid methyl ester analyses showed that most fatty acids were increased in L. acetotolerans F28 after exposure to ethanol while the unsaturated fatty acid octadecenoic acid (C18:1) was significantly increased. The increasing unsaturated fatty acid biosynthesis in L. acetotolerans F28 might enhance cell membrane fluidity and protect the cells against high concentration of ethanol. Overall, the transcriptome and functional analysis indicated that the elevated stress response and fatty acid biosynthesis, and the decrease of amino acid transport and metabolism might play important roles for L. acetotolerans F28 to adapt to environmental ethanol.
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