Evidence map›Paper›PMID 28572591›Full record

ArticleScientific reports2017

Morphologic and biometric evaluation of chick embryo eyes in ovo using 7 Tesla MRI.

Tobias Lindner, Ronja Klose, Felix Streckenbach, Thomas Stahnke, Stefan Hadlich, Jens-Peter Kühn, Rudolf F Guthoff, Andreas Wree, Anne-Marie Neumann, Marcus Frank and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Longitudinal volumetric analysis ofFrontiers in veterinary science · 2024
    Article
  5. Article
  6. In Ovo Sexing of Chicken Eggs by Virus Spectroscopy.Open access Macedonian journal of medical sciences · 2019
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Tobias LindnerCore Facility Multimodal Small Animal Imaging, Rostock University Medical Center, Rostock, Germany. tobias.lindner@med.uni-rostock.de.ORCID 0000-0001-7826-3132
Ronja KloseDepartment of Ophthalmology, Rostock University Medical Center, Rostock, Germany.
Felix StreckenbachDepartment of Ophthalmology, Rostock University Medical Center, Rostock, Germany.
Thomas StahnkeDepartment of Ophthalmology, Rostock University Medical Center, Rostock, Germany.
Stefan HadlichInstitute for Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany.
Jens-Peter KühnInstitute for Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany.
Rudolf F GuthoffDepartment of Ophthalmology, Rostock University Medical Center, Rostock, Germany.
Andreas WreeInstitute of Anatomy, Rostock University Medical Center, Rostock, Germany.
Anne-Marie NeumannInstitute of Anatomy, Rostock University Medical Center, Rostock, Germany.ORCID 0000-0001-5831-0608
Marcus FrankMedical Biology and Electron Microscopy Centre, Rostock University Medical Center, Rostock, Germany.ORCID 0000-0002-2517-4440
Änne GlassInstitute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Rostock, Germany.
Sönke LangnerInstitute for Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany.
Oliver StachsDepartment of Ophthalmology, Rostock University Medical Center, Rostock, Germany.
University of Rostock · DEUniversitätsmedizin Greifswald · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purposes of this study were (1) to characterize embryonic eye development during incubation in ovo and (2) to analyze the putative influence of repetitive ultrahigh-field MRI (UHF-MRI) measurements on this development. A population of 38 fertilized chicken eggs was divided into two sub-groups: two eggs (Group A) were examined repeatedly during the developmental period from embryonic day 1 (E1) to embryonic day 20 (E20) to evaluate the influence of daily MRI scanning. A second larger group of 36 eggs was examined pairwise on one day only, from E3 to E20, and the embryos were sacrificed immediately after MR imaging (Group B). Fast T2-weighted MR sequences provided biometric data on the eye with an in-plane resolution of 74 μm. The data show rapid growth of the eye with a steep increase in intraocular dimensions in all axis directions and in eyeball volume during initial development up to E10, followed by a phase of reduced growth rate in later developmental stages. Comparison of the two groups revealed no differences in ocular development.

Indexed as

Magnetic Resonance ImagingAnimalsBiometryChick EmbryoEyeImage Processing, Computer-Assisted

Identifiers

PMID28572591
PMCPMC5453995
OpenAlexW2619680503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.