ArticleJournal of applied physiology (Bethesda, Md. : 1985)2017
UBC-Nepal expedition: markedly lower cerebral blood flow in high-altitude Sherpa children compared with children residing at sea level.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- [Amplitude-integrated electroencephalography monitoring results of hospitalized neonates in plateau areas].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024Article
- To the extreme! How biological anthropology can inform exercise physiology in extreme environments.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · 2023Review
- Dynamic onset response of the internal carotid artery to hypercapnia is blunted in children compared with adults.Physiological reports · 2022Article
- UBC-Nepal Expedition: An experimental overview of the 2016 University of British Columbia Scientific Expedition to Nepal Himalaya.PloS one · 2018Observational
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8 authors.
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Abstract
Developmental cerebral hemodynamic adaptations to chronic high-altitude exposure, such as in the Sherpa population, are largely unknown. To examine hemodynamic adaptations in the developing human brain, we assessed common carotid (CCA), internal carotid (ICA), and vertebral artery (VA) flow and middle cerebral artery (MCA) velocity in 25 (9.6 ± 1.0 yr old, 129 ± 9 cm, 27 ± 8 kg, 14 girls) Sherpa children (3,800 m, Nepal) and 25 (9.9 ± 0.7 yr old, 143 ± 7 cm, 34 ± 6 kg, 14 girls) age-matched sea level children (344 m, Canada) during supine rest. Resting gas exchange, blood pressure, oxygen saturation and heart rate were assessed. Despite comparable age, height and weight were lower (both
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