Evidence map›Paper›PMID 28572494›Full record

ReviewJournal of applied physiology (Bethesda, Md. : 1985)2017

Erythrocyte purinergic signaling components underlie hypoxia adaptation.

Kaiqi Sun, Hong Liu, Anren Song, Jeanne M Manalo, Angelo D'Alessandro, Kirk C Hansen, Rodney E Kellems, Holger K Eltzschig, Michael R Blackburn, Robert C Roach and 1 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of applied physiology (Bethesda, Md. : 1985), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Article
  3. Creg1 Regulates Erythroid Development via TGF-β/Smad2-Klf1 Axis in Zebrafish.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Characterization of the NPurinergic signalling · 2020
    Article
  10. Review
  11. Review
  12. Metabonomics window into plateau hypoxia.The Journal of international medical research · 2019
    Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Kaiqi SunDepartment of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, Texas.
Hong LiuDepartment of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, Texas.
Anren SongDepartment of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, Texas.
Jeanne M ManaloDepartment of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, Texas.
Angelo D'AlessandroDepartment of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, Colorado.
Kirk C HansenDepartment of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, Colorado.
Rodney E KellemsDepartment of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, Texas.
Holger K EltzschigDepartment of Anesthesiology, The University of Texas Health Science Center at Houston, Houston, Texas; and.
Michael R BlackburnDepartment of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, Texas.
Robert C RoachAltitude Research Center, Department of Emergency Medicine, University of Colorado School of Medicine, Aurora, Colorado.
Yang XiaDepartment of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, Texas; yang.xia@uth.tmc.edu.
The University of Texas Health Science Center at Houston · USUniversity of Colorado Denver · US

Funding

Trangenic Mouse Breeding CoreP01HL114457 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI BLACKBURN, MICHAEL R · 2013 to 2017
$10.0M
Proton Pump Inhibitors for Perioperative Acute Kidney InjuryR01DK097075 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ELTZSCHIG, HOLGER K. · 2013 to 2017
$1.7M
Metabolites, Sickle Cell Disease, and Novel TherapeuticsR01HL113574 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI XIA, YANG · 2013 to 2016
$1.5M
Molecular insight of erythrocyte hypoxic metabolic reprogramming in chronic kidney diseaseR01HL137990 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI XIA, YANG · 2017 to 2018
$989k
NHLBI NIH HHS P01 HL114457NHLBI NIH HHS R01 HL113574NHLBI NIH HHS R01 HL137990NIDDK NIH HHS R01 DK097075
6 · The paper itself

Abstract

Erythrocytes are vital to human adaptation under hypoxic conditions because of their abundance in number and irreplaceable function of delivering oxygen (O

Indexed as

AcclimatizationAdaptation, PhysiologicalAdenosineAMP-Activated Protein KinasesAnimalsErythrocytesHumansHypoxiaOxygenSignal TransductionAdenosineAMP-Activated Protein KinasesOxygenadenosine signalingerythrocytehypoxia adaptationhypoxic memorysphingosine 1-phosphate

Identifiers

PMID28572494
PMCPMC5668449
OpenAlexW2621110850

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.