Evidence map›Paper›PMID 28572443›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2017

Prostaglandin E receptor-4 receptor mediates endothelial barrier-enhancing and anti-inflammatory effects of oxidized phospholipids.

Olga Oskolkova, Grzegorz Gawlak, Yufeng Tian, Yunbo Ke, Nicolene Sarich, Sophia Son, Katrin Andreasson, Valery N Bochkov, Anna A Birukova, Konstantin G Birukov

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Single hormone or synthetic agonist induces GProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  3. Review
  4. The Novel Role of Metabolism-Associated Molecular Patterns in Sepsis.Frontiers in cellular and infection microbiology · 2022
    Review
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  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Olga OskolkovaLung Injury Center, Section of Pulmonary and Critical Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, USA.
Grzegorz GawlakLung Injury Center, Section of Pulmonary and Critical Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, USA.
Yufeng TianLung Injury Center, Section of Pulmonary and Critical Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, USA.
Yunbo KeLung Injury Center, Section of Pulmonary and Critical Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, USA.
Nicolene SarichLung Injury Center, Section of Pulmonary and Critical Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, USA.
Sophia SonLung Injury Center, Section of Pulmonary and Critical Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, USA.
Katrin AndreassonDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA.
Valery N BochkovDepartment of Pharmaceutical Chemistry, University of Graz, Graz, Austria.
Anna A BirukovaLung Injury Center, Section of Pulmonary and Critical Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, USA.
Konstantin G BirukovLung Injury Center, Section of Pulmonary and Critical Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, USA; kbirukov@anes.umm.edu.
University of Illinois Chicago · USUniversity of Chicago · USResearch Center Pharmaceutical Engineering (Austria) · ATStanford University · USUniversity of Maryland, Baltimore · US

Funding

Control of Lung Permeability by Oxidized PhospholipidsR01HL076259 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI BIRUKOV, KONSTANTIN · 2004 to 2023
$6.8M
Molecular control of lung endothelial barrier function in ALIR01HL087823 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI BIRUKOV, KONSTANTIN · 2008 to 2020
$4.6M
Microtubule-associated regulation of acute lung injuryR01HL107920 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI BIRUKOVA, ANNA · 2011 to 2019
$2.8M
Differential mechano-signaling in vascular endothelium by varying degrees of mechanical stretch - Resubmission 01R01HL130431 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI BIRUKOVA, ANNA · 2016 to 2019
$1.6M
Microtubule control of septic inflammationR01GM114171 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI BIRUKOVA, ANNA · 2015 to 2018
$1.2M
Phospholipidomics and inflammation in sepsisR01GM122940 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI BIRUKOV, KONSTANTIN · 2017 to 2020
$1.2M
Microtubule-associated regulation of acute lung injuryR56HL107920 · NHLBI · UNIVERSITY OF CHICAGO · PI BIRUKOVA, ANNA · 2015 to 2015
$395k
NHLBI NIH HHS R01 HL076259NHLBI NIH HHS R01 HL087823NHLBI NIH HHS R01 HL107920NHLBI NIH HHS R01 HL130431NHLBI NIH HHS R56 HL107920NIGMS NIH HHS R01 GM114171NIGMS NIH HHS R01 GM122940
6 · The paper itself

Abstract

Unlike other agonists that cause transient endothelial cell (EC) response, the products of 1-palmitoyl-2-arachidonoyl-

Indexed as

Adherens JunctionsAnimalsCytoskeletonElectric ImpedanceEndothelial CellsHumansInflammationLung InjuryMiceMice, KnockoutOxidation-ReductionPhosphatidylcholinesPhospholipidsrac1 GTP-Binding ProteinReceptors, Prostaglandin E, EP4 SubtypeThrombin1-palmitoyl-2-arachidonyl-3-phosphorylcholinePhosphatidylcholinesPhospholipidsPtger4 protein, mouserac1 GTP-Binding ProteinReceptors, Prostaglandin E, EP4 SubtypeThrombinTumor Necrosis Factor-alphaacute lung injurycytoskeletonvascular permeability

Identifiers

PMID28572443
PMCPMC5572684
OpenAlexW2621170054

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.