Evidence map›Paper›PMID 28571528›Full record

ArticlePharmaceutical biology2017

Antioxidant activity against H

Xiliang Yang, Qingyun Peng, Qian Liu, Jie Hu, Zhipeng Tang, Lianjie Cui, Zonghao Lin, Bing Xu, Kuojian Lu, Fang Yang and 5 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Pharmaceutical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. PeerJ · 2024
    Article
  5. Review
  6. Review
  7. Phenolic Composition of the Leaves ofMolecules (Basel, Switzerland) · 2020
    Article
  8. Article
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Xiliang Yanga Department of Pharmacy , Medical College, Wuhan University of Science and Technology , Wuhan , China.
Qingyun Penga Department of Pharmacy , Medical College, Wuhan University of Science and Technology , Wuhan , China.
Qian Liua Department of Pharmacy , Medical College, Wuhan University of Science and Technology , Wuhan , China.
Jie Hua Department of Pharmacy , Medical College, Wuhan University of Science and Technology , Wuhan , China.
Zhipeng Tanga Department of Pharmacy , Medical College, Wuhan University of Science and Technology , Wuhan , China.
Lianjie Cuia Department of Pharmacy , Medical College, Wuhan University of Science and Technology , Wuhan , China.
Zonghao Lina Department of Pharmacy , Medical College, Wuhan University of Science and Technology , Wuhan , China.
Bing Xua Department of Pharmacy , Medical College, Wuhan University of Science and Technology , Wuhan , China.
Kuojian Lua Department of Pharmacy , Medical College, Wuhan University of Science and Technology , Wuhan , China.
Fang Yanga Department of Pharmacy , Medical College, Wuhan University of Science and Technology , Wuhan , China.
Zhizheng Shenga Department of Pharmacy , Medical College, Wuhan University of Science and Technology , Wuhan , China.
Qiong Yuana Department of Pharmacy , Medical College, Wuhan University of Science and Technology , Wuhan , China.
Song Liua Department of Pharmacy , Medical College, Wuhan University of Science and Technology , Wuhan , China.
Jiuliang Zhangb College of Food Science and Technology , Huazhong Agricultural University , Wuhan , China.
Xuefeng Zhouc Key Laboratory of Tropical Marine Bio-Resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica , South China Sea Institute of Oceanology, Chinese Academy of Sciences , Guangzhou , China.
Wuhan University of Science and Technology · CNChinese Academy of Sciences · CNHuazhong Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextThe leaves of Pyrola decorate H. Andr (Pyrolaceae), known as Luxiancao, have long been used for treating kidney deficiency, gastric haemorrhage and rheumatic arthritic diseases in traditional Chinese medicine.

objectiveThe phytochemicals and antioxidant capacities in vitro of P. decorate leaves were investigated. MATERIALS AND

methodsEthanol, petroleum ether, acetidin, n-butyl alcohol and aqueous extracts of Pyrola decorate leaves were prepared by solvent sequential process, and then isolated and purified to obtain phytochemicals. Cell viability was measured by MTT assay. PC12 cells were pretreated for 24 h with different extractions of P. decorate leaves at concentrations of 0.1, 0.5, 1, 5 and 10 mg/mL, then H

resultsNine compounds (1-9) were isolated and structurally determined by spectroscopic methods, especially 2D NMR analyses. Ethanol extract treated groups showed inhibitory activity with IC DISCUSSION AND

conclusionsIn conclusion, Pyrola decorate is a potential antioxidative natural plant and worth testing for further pharmacological investigation in the treatment of oxidative stress related neurological disease.

Indexed as

AnimalsAntioxidantsApoptosisBetulinic AcidCell Line, TumorCell SurvivalChinaEthanolEthnopharmacologyHydrogen PeroxideIridoidsMolecular StructureNeuronsNeuroprotective AgentsOxidantsOxidative StressAntioxidantsbetulinBetulinic AcidEthanolHydrogen PeroxideIridoidsmonotropeinNeuroprotective AgentsOxidantsPlant ExtractsSolventsTriterpenesUrsolic Acidisolationoxidative stressPyrolaceaeterpenoids

Identifiers

PMID28571528
PMCPMC6130655
OpenAlexW2621011961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.