Evidence map›Paper›PMID 28570673›Full record

ArticlePloS one2017

Determinants of adherence to recommendations for cancer prevention among Lynch Syndrome mutation carriers: A qualitative exploration.

Annemiek Visser, Alina Vrieling, Laxsini Murugesu, Nicoline Hoogerbrugge, Ellen Kampman, Meeke Hoedjes

Abstract readComparative Study
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Annemiek VisserRadboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.
Alina VrielingRadboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.
Laxsini MurugesuDepartment of Health Sciences, VU University Amsterdam, Amsterdam, the Netherlands.
Nicoline HoogerbruggeDepartment of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.
Ellen KampmanRadboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.
Meeke HoedjesDepartment of Health Sciences, VU University Amsterdam, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0001-6887-2882

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLynch Syndrome (LS) mutation carriers are at high risk for various cancer types, particularly colorectal cancer. Adherence to lifestyle and body weight recommendations for cancer prevention may lower this risk. To promote adherence to these recommendations, knowledge on determinants of adherence in LS mutation carriers is needed. Therefore, this study aimed to identify determinants of adherence to lifestyle recommendations for cancer prevention in LS mutation carriers.

methodsFive focus groups were conducted with DNA confirmed LS mutation carriers (n = 29). Transcripts were analyzed by thematic analysis, using the Health Belief Model (HBM) as a theoretical framework.

resultsTolerance of an unhealthy lifestyle because of the desire to enjoy life and avoidance of LS dominating their life were most frequently reported as important barriers of adherence to the recommendations. Most important facilitators of adherence to the recommendations were enhancement of wellbeing and intolerance of unhealthy foods due to colon surgery.

conclusionsThis study provided a comprehensive overview of determinants of adherence to recommendations for cancer prevention. These determinants, of which some are typically and unique for LS mutation carriers, can be used to design a lifestyle intervention that meets the needs of LS mutation carriers.

Indexed as

Genetic MarkersQuantitative Trait LociHumansGenetic Markers

Identifiers

PMID28570673
PMCPMC5453435

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.