ArticlePloS one2017
Loose Panicle1 encoding a novel WRKY transcription factor, regulates panicle development, stem elongation, and seed size in foxtail millet [Setaria italica (L.) P. Beauv.].
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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26 citing papers in PubMed, 54 citations in OpenAlex.
- Genetic linkage map construction and QTL mapping for panicle-related traits in foxtail millet (Molecular breeding : new strategies in plant improvement · 2025Article
- Foxtail millet research in supporting climate change resilience efforts: Bibliometric analysis and focused literature review.Heliyon · 2025Review
- Understanding the Molecular Regulatory Networks of Seed Size in Soybean.International journal of molecular sciences · 2024Review
- Panicle transcriptome of high-yield mutant indica rice reveals physiological mechanisms and novel candidate regulatory genes for yield under reproductive stage drought stress.BMC plant biology · 2023Article
- Identification and Investigation of the Genetic Variations and Candidate Genes Responsible for Seed Weight via GWAS in Paper Mulberry.International journal of molecular sciences · 2022Article
- Article
- Multi-omics intervention inFrontiers in plant science · 2022Review
- Conjunctive Analyses of Bulk Segregant Analysis Sequencing and Bulk Segregant RNA Sequencing to Identify Candidate Genes Controlling Spikelet Sterility of Foxtail Millet.Frontiers in plant science · 2022Article
- Overexpression ofGenes · 2021Article
- Genetic control and phenotypic characterization of panicle architecture and grain yield-related traits in foxtail millet (Setaria italica).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Transcription Factor TaWRKY51 Is a Positive Regulator in Root Architecture and Grain Yield Contributing Traits.Frontiers in plant science · 2021Article
- Transcriptome Analysis Reveals a Potential Role of Benzoxazinoid in Regulating Stem Elongation in the Wheat MutantFrontiers in genetics · 2021Article
- Genome-Wide DNA Polymorphism Analysis and Molecular Marker Development for theFrontiers in plant science · 2021Article
- Transcriptome Analysis Reveals Key Pathways and Candidate Genes Controlling Seed Development and Size in Ricebean (Frontiers in genetics · 2021Article
- Transcriptome Analysis Provides Insights into Grain Filling in Foxtail Millet (International journal of molecular sciences · 2020Article
- Identification of QTLs for Domestication-Related Traits in Zombi Pea [Frontiers in genetics · 2020Article
- Article
- Understanding the Role of the WRKY Gene Family under Stress Conditions in Pigeonpea (Plants (Basel, Switzerland) · 2019Article
- SiSTL1, encoding a large subunit of ribonucleotide reductase, is crucial for plant growth, chloroplast biogenesis, and cell cycle progression in Setaria italica.Journal of experimental botany · 2019Article
- The Cotton GhWRKY91 Transcription Factor Mediates Leaf Senescence and Responses to Drought Stress in TransgenicFrontiers in plant science · 2019Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Panicle development is an important agronomic trait that aids in determining crop productivity. Foxtail millet and its wild ancestor green foxtail have recently been used as model systems to dissect gene functions. Here, we characterized a recessive mutant of foxtail millet, loose-panicle 1 (lp1), which showed pleiotropic phenotypes, such as a lax primary branching pattern, aberrant branch morphology, semi-dwarfism, and enlarged seed size. The loose panicle phenotype was attributed to increased panicle lengths and decreased primary branch numbers. Map-based cloning, combined with high-throughput sequencing, revealed that LP1, which encodes a novel WRKY transcription factor, is responsible for the mutant phenotype. A phylogenetic analysis revealed that LP1 belongs to the Group I WRKY subfamily, which possesses two WRKY domains (WRKY I and II). A single G-to-A transition in the fifth intron of LP1 resulted in three disorganized splicing events in mutant plants. For each of these aberrant splice variants, the normal C2H2 motif in the WRKY II domain was completely disrupted, resulting in a loss-of-function mutation. LP1 mRNA was expressed in all of the tissues examined, with higher expression levels observed in inflorescences, roots, and seeds at the grain-filling stage. A subcellular localization analysis showed that LP1 predominantly accumulated in the nucleus, which confirmed its role as a transcriptional regulator. This study provides novel insights into the roles of WRKY proteins in regulating reproductive organ development in plants and may help to develop molecular markers associated with crop yields.
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