ArticleOtology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology2017
Inflammatory Pseudotumor of the Temporal Bone: A Case Series.
Article in Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 24 citations in OpenAlex.
- Benign paratesticular inflammatory pseudotumor: A rare case report.Radiology case reports · 2025Article
- Bone destruction of orbital wall in idiopathic orbital inflammatory pseudotumor: does it always imply malignancy?International journal of ophthalmology · 2024Article
- Article
- Inflammatory Myofibroblastic Tumor: Two Cases in Head and Neck Region.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022Article
- Treatment and Prognosis of Inflammatory Pseudotumor of the Skull Base.Journal of neurological surgery. Part B, Skull base · 2022Article
- Labyrinthine destruction caused by inflammatory pseudotumor of the temporal bone: A report of three cases and review of the literature.Laryngoscope investigative otolaryngology · 2021Article
- Tumefactive fibroinflammatory lesion of the maxilla: Successful resection and microvascular reconstruction after failed medical therapy.Oral and maxillofacial surgery · 2021Article
- Tumefactive fibroinflammatory lesion successfully treated with Rituximab.Intractable & rare diseases research · 2019Article
- Fibrosing Inflammatory Pseudotumor Presenting as Cranial Neuropathy.Case reports in neurologyArticle
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
objectiveInflammatory pseudotumor of the temporal bone is a benign, idiopathic inflammatory process that is locally invasive and a cause of significant morbidity. This study reviews our experience with seven patients and is currently the largest series to date. STUDY
designRetrospective review from January 1, 2014 to January 1, 2016.
settingSingle tertiary medical center. PATIENTS: There were five male and two female (n = 7) subjects with a diagnosis of temporal bone inflammatory pseudotumor. The mean age at presentation was 41 years old. The most common presenting symptoms were hearing loss (7/7) and headache (4/7). Four patients demonstrated an inflammatory aural polyp. Two patients experienced facial nerve paralysis. INTERVENTION(S): Seven patients underwent computed tomography and six underwent magnetic resonance imaging. Corticosteroids and antibiotics were the initial treatment of choice. Five patients also underwent surgery. As adjuvant therapy, two patients received Rituximab, one patient received radiation, and one received mycophenolate mofetil. MAIN OUTCOME MEASURE(S): Clinical courses were followed with focus on symptoms, disease recurrence, duration, and treatment. Mean follow-up was 17.8 months.
resultsThe primary lesions demonstrated T2 hypo-intensity and enhancement as well as diffuse dural thickening on magnetic resonance imaging in five of six patients. Histopathology demonstrated chronic inflammation in the setting of hyalinized fibrosis (7/7). All the patients are currently symptomatically stable.
conclusionInflammatory pseudotumor of the temporal bone can cause devastating effects on neurological function and quality of life. Recognition of characteristic imaging and histopathology can expedite appropriate treatment. Patients may require chronic steroid therapy. Adjunctive therapy with radiation and immuno-modulation are currently being explored.
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