Evidence map›Paper›PMID 28570388›Full record

SynthesisEpidemiology (Cambridge, Mass.)2017

Effort-Reward Imbalance at Work and Incident Coronary Heart Disease: A Multicohort Study of 90,164 Individuals.

Nico Dragano, Johannes Siegrist, Solja T Nyberg, Thorsten Lunau, Eleonor I Fransson, Lars Alfredsson, Jakob B Bjorner, Marianne Borritz, Hermann Burr, Raimund Erbel and 26 more

Registry-linked trialOpen access · hybridAbstract readMeta-AnalysisMulticenter StudyReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Epidemiology (Cambridge, Mass.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04386135 (DESVELA Cohort. Analysis of the Role of Personal Skills as Determinants of Incidence of Morbidity, Lifestyles, Quality of Life, Use of Services and Mortality.), which is not on this map. Cited by 138 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed, 8 pooled it
59.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04386135 unknown statusnot on this mapstarted 2021, after this paper: background citation

DESVELA Cohort. Analysis of the Role of Personal Skills as Determinants of Incidence of Morbidity, Lifestyles, Quality of Life, Use of Services and Mortality.

TypeobservationalSponsorFundacio d'Investigacio en Atencio Primaria Jordi Gol i GurinaRan2021 to 2025Enrolled3,260ConditionsGeneral Population, Health Knowledge, Attitudes, Practice, Empowerment, Health Care Utilization
3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 8 syntheses or guidelines pooled it, 300 citations in OpenAlex.

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  8. Work-related stress as a cardiovascular risk factor in police officers: a systematic review of evidence.International archives of occupational and environmental health · 2018
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78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

36 authors at 20 institutions in 7 countries.

Nico DraganoFrom the aInstitute of Medical Sociology, Medical Faculty, University of Düsseldorf, Düsseldorf, Germany; bClinicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland; cInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; dSchool of Health Sciences, Jönköping University, Jönköping, Sweden; eStress Research Institute, Stockholm University, Stockholm, Sweden; fCentre for Occupational and Environmental Medicine, Stockholm County Council, Sweden; gNational Research Centre for the Working Environment, Copenhagen, Denmark; hUnit of Social Medicine, Frederiksberg University Hospital, Copenhagen, Denmark; iFederal Institute for Occupational Safety and Health (BAuA), Berlin, Germany; jInstitute for Medical Informatics, Biometry, and Epidemiology, Faculty of Medicine, University Duisburg-Essen, Essen, Germany; kThe National Agency for Special Needs Education and Schools, Härnösand, Sweden; lParis Descartes University, Paris, France; mInserm U1018, University Paris Saclay, France; nDepartment of Epidemiology and Public Health, University College London, London, United Kingdom; oSchool of Sport, Exercise and Health Sciences, University of Loughborough, Loughborough, United Kingdom; pDepartment of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom; qClinical Effectiveness Unit, The Royal College of Surgeons, London, United Kingdom; rDepartment of Health Sciences, Mid Sweden University, Sundsvall, Sweden; sAS3 Employment, AS3 Companies, Viby J, Denmark; tDepartment of Psychology, Umeå University, Umeå, Sweden; uFinnish Institute of Occupational Health, Helsinki, Tampere and Turku, Finland; vThe Danish National Centre for Social Research, Copenhagen, Denmark; wDepartment of Public Health and Department of Psychology, University of Copenhagen, Copenhagen, Denmark; xDepartment of Psychology, University of Turku, Turku, Finland; yGerman Institute for Economic Research, Berlin, Germany; zDepartment of Public Health, University of Turku, Turku, Finland; aaTurku University Hospital, Turku, Finland; bbOccupational and Environmental Medicine, Uppsala University, Uppsala, Sweden.
Johannes Siegrist
Solja T Nyberg
Thorsten Lunau
Eleonor I Fransson
Lars Alfredsson
Jakob B Bjorner
Marianne Borritz
Hermann Burr
Raimund Erbel
Göran Fahlén
Marcel Goldberg
Mark Hamer
Katriina Heikkilä
Karl-Heinz Jöckel
Anders Knutsson
Ida E H Madsen
Martin L Nielsen
Maria Nordin
Tuula Oksanen
Jan H Pejtersen
Jaana Pentti
Reiner Rugulies
Paula Salo
Jürgen Schupp
Archana Singh-Manoux
Andrew Steptoe
Töres Theorell
Jussi Vahtera
Peter J M Westerholm
Hugo Westerlund
Marianna Virtanen
Marie Zins
G David Batty
Mika Kivimäki
IPD-Work consortium
Stockholm University · SEFinnish Institute of Occupational Health · FIUniversity College London · GBUniversity of Helsinki · FIDélégation Paris 5 · FRHeinrich Heine University Düsseldorf · DENational Research Centre for the Working Environment · DKUniversity of Duisburg-Essen · DEUniversity of Turku · FIDanish National Centre for Social Research · DKEmployment Agency · BGFederal Institute for Occupational Safety and Health · DEFrederiksberg Hospital · DKGerman Institute for Economic Research · DEInserm · FRLoughborough University · GBMid Sweden University · SERoyal College of Surgeons of England · GBSpecialpedagogiska Skolmyndigheten · SEStockholm County Council · SE

Funding

British Heart FoundationMedical Research Council MR/K013351/1
6 · The paper itself

Abstract

backgroundEpidemiologic evidence for work stress as a risk factor for coronary heart disease is mostly based on a single measure of stressful work known as job strain, a combination of high demands and low job control. We examined whether a complementary stress measure that assesses an imbalance between efforts spent at work and rewards received predicted coronary heart disease.

methodsThis multicohort study (the "IPD-Work" consortium) was based on harmonized individual-level data from 11 European prospective cohort studies. Stressful work in 90,164 men and women without coronary heart disease at baseline was assessed by validated effort-reward imbalance and job strain questionnaires. We defined incident coronary heart disease as the first nonfatal myocardial infarction or coronary death. Study-specific estimates were pooled by random effects meta-analysis.

resultsAt baseline, 31.7% of study members reported effort-reward imbalance at work and 15.9% reported job strain. During a mean follow-up of 9.8 years, 1,078 coronary events were recorded. After adjustment for potential confounders, a hazard ratio of 1.16 (95% confidence interval, 1.00-1.35) was observed for effort-reward imbalance compared with no imbalance. The hazard ratio was 1.16 (1.01-1.34) for having either effort-reward imbalance or job strain and 1.41 (1.12-1.76) for having both these stressors compared to having neither effort-reward imbalance nor job strain.

conclusionsIndividuals with effort-reward imbalance at work have an increased risk of coronary heart disease, and this appears to be independent of job strain experienced. These findings support expanding focus beyond just job strain in future research on work stress.

Indexed as

RewardAdultAge FactorsCohort StudiesCoronary DiseaseEuropeFemaleHumansIncidenceInternationalityJob SatisfactionMaleMiddle AgedOccupational DiseasesProportional Hazards ModelsRisk Factors

Identifiers

PMID28570388
PMCPMC5457838
OpenAlexW2601011086

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.