Evidence map›Paper›PMID 28570148›Full record

ArticleAnnals of the American Thoracic Society2017

An Official American Thoracic Society Workshop Report: Obesity and Metabolism. An Emerging Frontier in Lung Health and Disease.

Benjamin T Suratt, Niki D J Ubags, Deepa Rastogi, Kelan G Tantisira, Benjamin J Marsland, Irina Petrache, Janice B Allen, Jason H T Bates, Fernando Holguin, Meredith C McCormack and 12 more

Abstract read
In one paragraph

Article in Annals of the American Thoracic Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Diabetes-inducing effects of bronchial asthma.World journal of diabetes · 2025
    Article
  5. Oxysterols in Infectious Diseases.Advances in experimental medicine and biology · 2024
    Article
  6. Endogenous and Therapeutic 25-Hydroxycholesterols May Worsen Early SARS-CoV-2 Pathogenesis in Mice.American journal of respiratory cell and molecular biology · 2023
    Article
  7. Static respiratory mechanics are unaltered in males and females with obesity.Journal of applied physiology (Bethesda, Md. : 1985) · 2023
    Article
  8. Review
  9. Metformin prevents airway hyperreactivity in rats with dietary obesity.American journal of physiology. Lung cellular and molecular physiology · 2021
    Article
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Childhood Obesity and Respiratory Diseases: Which Link?Children (Basel, Switzerland) · 2021
    Review
  15. Article
  16. Hospitalizations and Deaths Associated with EVALI.The New England journal of medicine · 2020
    Article
  17. Article
  18. Review
  19. Metabolic Dysfunction and Asthma: Current Perspectives.Journal of asthma and allergy · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 1 institution in 1 country.

Niki D J Ubags
Deepa Rastogi
Kelan G Tantisira
Benjamin J Marsland
Irina Petrache
Janice B Allen
Jason H T Bates
Fernando Holguin
Meredith C McCormack
Evangelos D Michelakis
Stephen M Black
Manu Jain
Ana L Mora
Viswanathan Natarajan
Yury I Miller
Michael B Fessler
Konstantin G Birukov
Ross S Summer
Stephanie A Shore
Anne E Dixon
Allergy, Immunology, and Inflammation Assembly
University of Vermont · US

Funding

Cell Signaling of Host DefenseZIAES102005 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI FESSLER, MICHAEL B · 2009 to 2025
$41.7M
Ceramide-induced Lung Destruction in EmphysemaR01HL077328 · NHLBI · NATIONAL JEWISH HEALTH · PI PETRACHE, IRINA · 2006 to 2024
$8.0M
PERINATAL REGULATION OF THE ENDOTHELIAL NOS GENER01HL060190 · NHLBI · UNIVERSITY OF MONTANA · PI Stephen M Black · 1998 to 2026
$7.1M
Control of Lung Permeability by Oxidized PhospholipidsR01HL076259 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI BIRUKOV, KONSTANTIN · 2004 to 2023
$6.8M
Impact of Obesity on Airway Responses to Air PollutionR01ES013307 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SHORE, STEPHANIE A · 2005 to 2019
$5.2M
The role of obesity in biological responses to particulate matter in miceP50ES018176 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI HANSEL, NADIA N · 2015 to 2019
$4.8M
The Environmental Assessments Core (FSC)P50MD010431 · NIMHD · JOHNS HOPKINS UNIVERSITY · PI MATSUI, ELIZABETH C. · 2015 to 2019
$3.5M
MICRORNAS IN CIRCULATION: ONTOLOGIES OF ASTHMA SEVERITY AND TREATMENT (MICROCOAST)R01HL127332 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI TANTISIRA, KELAN G · 2015 to 2018
$3.4M
Cell Signaling of Host DefenseZ01ES102005 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI FESSLER, MICHAEL B · 2006 to 2008
$3.3M
Non-Allergic Late-Onset Asthma of Obesity: Pathophysiology and TherapyR01HL130847 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI BATES, JASON HT, DIXON, ANNE E · 2016 to 2019
$2.3M
Reciprocal regulation of SDF-1 between marrow and lung during acute lung injuryR01HL084200 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI SURATT, BENJAMIN T · 2006 to 2010
$2.0M
Adiponectin inhibits activation and injury of lung endotheliumR01HL105490 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI SUMMER, ROSS S · 2011 to 2015
$1.9M
Intramural NIH HHS Z01 ES102005NHLBI NIH HHS K23 HL118733NHLBI NIH HHS R01 HL060190NHLBI NIH HHS R01 HL076259NHLBI NIH HHS R01 HL077328NHLBI NIH HHS R01 HL084200NHLBI NIH HHS R01 HL105490NHLBI NIH HHS R01 HL124174NHLBI NIH HHS R01 HL127332NHLBI NIH HHS R01 HL130847NHLBI NIH HHS R01 HL131789NIAID NIH HHS R03 AI117069NIEHS NIH HHS P50 ES018176NIEHS NIH HHS R01 ES013307NIEHS NIH HHS R21 ES024032NIMHD NIH HHS P50 MD010431
6 · The paper itself

Abstract

The world is in the midst of an unprecedented epidemic of obesity. This epidemic has changed the presentation and etiology of common diseases. For example, steatohepatitis, directly attributable to obesity, is now the most common cause of cirrhosis in the United States. Type 2 diabetes is increasingly being diagnosed in children. Pulmonary researchers and clinicians are just beginning to appreciate the impact of obesity and altered metabolism on common pulmonary diseases. Obesity has recently been identified as a major risk factor for the development of asthma and for acute respiratory distress syndrome. Obesity is associated with profound changes in pulmonary physiology, the development of pulmonary hypertension, sleep-disordered breathing, and altered susceptibility to pulmonary infection. In short, obesity is leading to dramatic changes in lung health and disease. Simultaneously, the rapidly developing field of metabolism, including mitochondrial function, is shifting the paradigms by which the pathophysiology of many pulmonary diseases is understood. Altered metabolism can lead to profound changes in both innate and adaptive immunity, as well as the function of structural cells. To address this emerging field, a 3-day meeting on obesity, metabolism, and lung disease was convened in October 2015 to discuss recent findings, foster research initiatives, and ultimately guide clinical care. The major findings arising from this meeting are reported in this document.

Indexed as

AdultChildDiabetes Mellitus, Type 2HumansLungLung DiseasesObesitySleep Apnea SyndromesSocieties, MedicalUnited States

Identifiers

PMID28570148
PMCPMC5802569
OpenAlexW2621256156

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.