ArticleJournal of the American Chemical Society2017
Palladium-Catalyzed Cross-Coupling of Silyl Electrophiles with Alkylzinc Halides: A Silyl-Negishi Reaction.
Article in Journal of the American Chemical Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- A DMAP-enabled strategy for C(spNature communications · 2025Article
- Catalytic Reactions Involving the Oxidative Addition of Si─Halogen and Si─Pseudohalogen Bonds as a Key Step.Chemistry, an Asian journal · 2025Review
- The role of silicon in drug discovery: a review.RSC medicinal chemistry · 2024Review
- Enantioselective and Regiodivergent Synthesis of Propargyl- and Allenylsilanes through Catalytic Propargylic C-H Deprotonation.Angewandte Chemie (International ed. in English) · 2024Article
- Constrained Phosphine Chalcogenide Selenoethers Supported byMolecules (Basel, Switzerland) · 2023Article
- Facile preparation of organosilanes from benzylboronates andChemical science · 2023Article
- Regioselective Ni-Catalyzed reductive alkylsilylation of acrylonitrile with unactivated alkyl bromides and chlorosilanes.Nature communications · 2022Article
- Direct synthesis and applications of solid silylzinc reagents.Chemical science · 2021Article
- Nickel-Catalyzed, Reductive C(spAngewandte Chemie (International ed. in English) · 2021Article
- Synthesis ofMolecules (Basel, Switzerland) · 2021Article
- Stereoselective Synthesis ofJournal of the American Chemical Society · 2020Article
- Stereospecific and Chemoselective Copper-Catalyzed Deaminative Silylation of Benzylic Ammonium Triflates.Angewandte Chemie (International ed. in English) · 2020Article
- Synthesis of Unsaturated Silyl HeterocyclesOrganometallics · 2019Article
- Catalyst-controlled regiodivergent ring-opening C(spChemical science · 2019Article
- Selective Arene Hydrogenation for Direct Access to Saturated Carbo- and Heterocycles.Angewandte Chemie (International ed. in English) · 2019Review
- Cross-Coupling of Heteroatomic Electrophiles.Chemical reviews · 2019Review
- Cobalt-catalyzed difluoroalkylation of tertiary aryl ketones for facile synthesis of quaternary alkyl difluorides.Nature communications · 2018Article
- Copper-catalyzed enantioselective 1,2-borylation of 1,3-dienes.Chemical science · 2018Article
- Palladium-Catalyzed Cross-Coupling of Monochlorosilanes And Grignard Reagents.ACS catalysis · 2017Article
- A Bench-Stable, Single-Component Precatalyst for Silyl-Heck Reactions.Organic letters · 2017Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
We report the first example of a silyl-Negishi reaction between secondary zinc organometallics and silicon electrophiles. This palladium-catalyzed process provides direct access to alkyl silanes. The delicate balance of steric and electronic parameters of the employed DrewPhos ligand is paramount to suppressing isomerization and promoting efficient and selective cross-coupling.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.