Evidence map›Paper›PMID 28569760›Full record

ArticleNature communications2017

Strength of Neisseria meningitidis binding to endothelial cells requires highly-ordered CD147/β

Nawal Maïssa, Valentina Covarelli, Sébastien Janel, Beatrice Durel, Nandi Simpson, Sandra C Bernard, Liliana Pardo-Lopez, Haniaa Bouzinba-Ségard, Camille Faure, Mark G H Scott and 6 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Article
  3. CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Frontiers in cellular and infection microbiology · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. The Host-Pathogen Interactions and Epicellular Lifestyle ofFrontiers in cellular and infection microbiology · 2022
    Review
  16. Mechanical Activation of the βFrontiers in endocrinology · 2022
    Review
  17. Article
  18. The minor pilin PilV provides a conserved adhesion site throughout the antigenically variable meningococcal type IV pilus.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  19. Review
  20. Mechanical GPCR Activation by Traction Forces Exerted on ReceptorACS pharmacology & translational science · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Nawal MaïssaInserm, U1016, Department of Infection, Immunity and Inflammation, Institut Cochin, 75014 Paris, France.
Valentina CovarelliInserm, U1016, Department of Infection, Immunity and Inflammation, Institut Cochin, 75014 Paris, France.
Sébastien JanelCellular Microbiology and Physics of infection, Center for Infection and Immunity of Lille, Institut Pasteur de Lille, 59000 Lille, France.
Beatrice DurelInserm, U1016, Department of Infection, Immunity and Inflammation, Institut Cochin, 75014 Paris, France.
Nandi SimpsonInserm, U1016, Department of Infection, Immunity and Inflammation, Institut Cochin, 75014 Paris, France.
Sandra C BernardInserm, U1016, Department of Infection, Immunity and Inflammation, Institut Cochin, 75014 Paris, France.
Liliana Pardo-LopezInserm, U1016, Department of Infection, Immunity and Inflammation, Institut Cochin, 75014 Paris, France.
Haniaa Bouzinba-SégardInserm, U1016, Department of Infection, Immunity and Inflammation, Institut Cochin, 75014 Paris, France.
Camille FaureInserm, U1016, Department of Infection, Immunity and Inflammation, Institut Cochin, 75014 Paris, France.
Mark G H ScottInserm, U1016, Department of Infection, Immunity and Inflammation, Institut Cochin, 75014 Paris, France.
Mathieu CoureuilInserm, unité U1151, Institut-Necker-Enfants-Malades, 75015 Paris, France.
Philippe C MorandInserm, U1016, Department of Infection, Immunity and Inflammation, Institut Cochin, 75014 Paris, France.
Frank LafontCellular Microbiology and Physics of infection, Center for Infection and Immunity of Lille, Institut Pasteur de Lille, 59000 Lille, France.
Xavier NassifInserm, unité U1151, Institut-Necker-Enfants-Malades, 75015 Paris, France.
Stefano MarulloInserm, U1016, Department of Infection, Immunity and Inflammation, Institut Cochin, 75014 Paris, France.ORCID 0000-0001-9604-9973
Sandrine BourdoulousInserm, U1016, Department of Infection, Immunity and Inflammation, Institut Cochin, 75014 Paris, France.
Délégation Paris 5 · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neisseria meningitidis (meningococcus) is an invasive bacterial pathogen that colonizes human vessels, causing thrombotic lesions and meningitis. Establishment of tight interactions with endothelial cells is crucial for meningococci to resist haemodynamic forces. Two endothelial receptors, CD147 and the β2-adrenergic receptor (β

Indexed as

ActininBacterial AdhesionBasiginEndothelial CellsHost-Pathogen InteractionsHumansMultiprotein ComplexesNeisseria meningitidisReceptors, Adrenergic, beta-2ActininACTN4 protein, humanADRB2 protein, humanBasiginBSG protein, humanMultiprotein ComplexesReceptors, Adrenergic, beta-2

Identifiers

PMID28569760
PMCPMC5461506
OpenAlexW2621114231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.