Evidence map›Paper›PMID 28569739›Full record

ArticleClinical and translational gastroenterology2017

Endoscopic-Guided Measurement of Mucosal Admittance can Discriminate Gastroesophageal Reflux Disease from Functional Heartburn.

Tomoaki Matsumura, Hideaki Ishigami, Mai Fujie, Takashi Taida, Shingo Kasamatsu, Kenichiro Okimoto, Keiko Saito, Daisuke Maruoka, Tomoo Nakagawa, Takeshi Suzuki and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Novel Technique to Diagnose Gastroesophageal Reflux Disease.The Korean journal of helicobacter and upper gastrointestinal research · 2024
    Review
  5. Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Tomoaki MatsumuraDepartment of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Hideaki IshigamiDepartment of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Mai FujieDepartment of Clinical Engineering Center, Chiba University Hospital, Chiba, Japan.
Takashi TaidaDepartment of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Shingo KasamatsuDepartment of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Kenichiro OkimotoDepartment of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Keiko SaitoDepartment of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Daisuke MaruokaDepartment of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Tomoo NakagawaDepartment of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Takeshi SuzukiDepartment of Otorhinolaryngology, Head and Neck Surgery, Chiba University, Chiba, Japan.
Tatsuro KatsunoDepartment of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Makoto AraiDepartment of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Chiba University · JPChiba University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesA novel catheter that can measure mucosal admittance (MA), the inverse of impedance, was developed recently. In this pilot study, we aimed to clarify the usefulness of measuring MA for diagnosing gastroesophageal reflux disease (GERD).

methodsWe conducted two prospective studies. In the first study, esophageal MA was evaluated in 120 participants (24 with erosive esophagitis, 82 with heartburn but non-erosive esophagitis, and 14 healthy volunteers) and compared with the endoscopic findings. In the second study, multichannel intraluminal impedance combined with pH (MII-pH) tests was conducted followed by an MA measurement in 33 patients with non-erosive esophagitis and proton pump inhibitor (PPI)-refractory heartburn. Based on the MII-pH test results, patients were divided into GERD or functional heartburn (FH). MA was compared between the GERD and FH groups and also compared with the baseline impedance (BI) and acid exposure time (AET).

resultsMedian MA at the distal esophagus was significantly higher in patients with erosive esophagitis compared with that in patients with non-erosive esophagitis and healthy volunteers (46.8, 13.1 and 6.5, respectively, P<0.01). In patients with PPI-refractory heartburn, the median MA at the distal esophagus was significantly higher in patients with GERD than those with FH (19.3 vs. 7.2, P<0.05). There was a negative correlation between MA and BI, and a positive correlation between MA and AET at the distal esophagus (r=-0.46 and r=0.53, P<0.05).

conclusionsReal-time measurement of MA is useful to distinguish GERD from non-GERD.

Identifiers

PMID28569739
PMCPMC5518945
OpenAlexW2621341730

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.