Evidence map›Paper›PMID 28569383›Full record

ReviewJournal of cardiovascular electrophysiology2017

Atrial fibrillation, cognition and dementia: A review.

Summer Aldrugh, Mayank Sardana, Nils Henninger, Jane S Saczynski, David D McManus

Open access · greenAbstract readReview
In one paragraph

Review in Journal of cardiovascular electrophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Atrial Fibrillation and Other Cardiovascular Factors and the Risk of Dementia: An Italian Case-Control Study.International journal of environmental research and public health · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Atrial cardiopathy and cognitive impairment.Frontiers in aging neuroscience · 2022
    Review
  17. Article
  18. Observational
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Summer AldrughDepartment of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.
Mayank SardanaDivision of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.ORCID http://orcid.org/0000-0001-9465-1047
Nils HenningerDepartment of Neurology, University of Massachusetts Medical School, Worcester, MA, USA.
Jane S SaczynskiDepartment of Pharmacy and Health System Sciences, Northeastern University, Boston, MA.
David D McManusDivision of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.
University of Massachusetts Chan Medical School · USNortheastern University · US

Funding

University of Massachusetts Center for Clinical Science and Translational SupplementUL1TR001453 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2015 to 2024
$39.0M
Systematic Assessment of Geriatric Elements in Atrial Fibrillation (SAGE-AF)R01HL126911 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MCMANUS, DAVID D., SACZYNSKI, JANE STEELE · 2016 to 2019
$3.2M
University of Massachusetts Center for Clinical and Translational ScienceKL2RR031981 · NCRR · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SULLIVAN, JOHN LEWIS · 2010 to 2011
$1.2M
Extracellular RNAs: Biomarkers for Cardiovascular Risk and DiseaseUH2TR000921 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI FREEDMAN, JANE E · 2013 to 2014
$1.0M
Inhibiting axon degeneration in a mouse model of acute brain injury through deletion of Sarm1K08NS091499 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI HENNINGER, NILS · 2016 to 2020
$919k
Medical Illness & Cognitive Impairment in Older Adults: Heart Failure as a ModelK01AG033643 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SACZYNSKI, JANE STEELE · 2010 to 2014
$628k
Arrhythmia Detection Using a Smart PhoneR15HL121761 · NHLBI · WORCESTER POLYTECHNIC INSTITUTE · PI CHONG, JO WOON · 2014 to 2014
$389k
NCATS NIH HHS UH2 TR000921NCATS NIH HHS UL1 TR001453NCRR NIH HHS KL2 RR031981NHLBI NIH HHS R01 HL126911NHLBI NIH HHS R15 HL121761NIA NIH HHS K01 AG033643NINDS NIH HHS K08 NS091499
6 · The paper itself

Abstract

Atrial fibrillation (AF) is one of the most common types of cardiac arrhythmia, particularly among older adults. AF confers a 5-fold risk for thromboembolic stroke as well as a 2-fold higher risk for congestive heart failure, morbidity, and mortality. Although stroke remains an important and impactful complication of AF, recent studies have shown that AF is independently associated with other neurological disorders, including cognitive impairment and dementia, even after adjusting for prior ischemic stroke. We performed a review of the published literature on the association between AF and cognitive status. Further, we reviewed studies investigating the underlying mechanisms for this association and/or reporting the impact of AF treatment on cognitive function. While most published studies demonstrate associations between AF and impaired cognition, no AF treatment has yet been associated with a reduced incidence of cognitive decline or dementia.

Indexed as

AnticoagulantsAtrial FibrillationCatheter AblationCognition DisordersDementiaHumansAnticoagulantsAlzheimer's diseaseanticoagulantsatrial fibrillationcognitive declinedementiavascular dementia

Identifiers

PMID28569383
PMCPMC5783292
OpenAlexW2620906688

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.