Evidence map›Paper›PMID 28569361›Full record

Trial reportObesity surgery2017

Hypertrophic Scars: Are Vitamins and Inflammatory Biomarkers Related with the Pathophysiology of Wound Healing?

Inês Correia-Sá, Paula Serrão, Marisa Marques, Maria A Vieira-Coelho

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Obesity surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Inês Correia-SáDepartment of Plastic, Reconstructive and Aesthetic Surgery, Maxillofacial Surgery and Burn Unit, Centro Hospitalar de São João, EPE, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal. inescsa@gmail.com.ORCID http://orcid.org/0000-0002-3731-8683
Paula SerrãoDepartment of Pharmacology & Therapeutics, Faculty of Medicine, University of Oporto, Porto, Portugal.
Marisa MarquesDepartment of Plastic, Reconstructive and Aesthetic Surgery, Maxillofacial Surgery and Burn Unit, Centro Hospitalar de São João, EPE, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal.
Maria A Vieira-CoelhoDepartment of Pharmacology & Therapeutics, Faculty of Medicine, University of Oporto, Porto, Portugal.

Funding

FCT PTDC/DTP-FTO/1018/2014
6 · The paper itself

Abstract

backgroundHypertrophic scars are a consequence of wound healing.

objectiveThe objective of the present study is to evaluate vitamin D and inflammatory biomarker plasma levels during wound healing.

methodsA prospective study was performed in patients (n = 63) submitted to body contouring surgery. Blood samples were collected before (t

resultsAt the end of the study, 73% of the patients developed a normal scar (control group, n = 46) and 27% of the patients presented hypertrophic scars (HT group, n = 17). The patients in the HT group presented higher eosinophil (0.145 × 10

conclusionThere is a different systemic inflammatory profile response in the patients during the formation of hypertrophic scars. Vitamin D plasma levels are marked reduced in these patients. Considering the powerful anti-inflammatory effect of vitamin D, these findings could be related.

Indexed as

AdultAgedBiomarkersBody ContouringCase-Control StudiesCicatrix, HypertrophicFemaleHumansInflammationMaleMiddle AgedObesityVitaminsWound HealingYoung AdultBiomarkersVitaminsBariatricHypertrophicInflammationScarVitamin DWound healing

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.