ArticleMicrobiome2017
Bacteriophage-prokaryote dynamics and interaction within anaerobic digestion processes across time and space.
Article in Microbiome, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed.
- Substrate-driven phage community structure and phage-host dynamics in anaerobic digesters.Environmental microbiome · 2026Article
- Decoding phage communication: molecular networks, evolutionary dynamics, and therapeutic applications.NPJ biofilms and microbiomes · 2026Review
- Functional gut microbiomes enhance performance in house fly larvae.Applied and environmental microbiology · 2026Article
- Viral and eukaryotic drivers of prokaryotic and antibiotic resistance gene diversity in wastewater microbiomes.Microbiome · 2026Article
- VISTA: A Tool for Fast Taxonomic Assignment of Viral Genome Sequences.Genomics, proteomics & bioinformatics · 2025Article
- Experimental warming accelerates positive soil priming in a temperate grassland ecosystem.Nature communications · 2024Article
- The structure and assembly mechanisms of T4-like cyanophages community in the South China Sea.Microbiology spectrum · 2024Article
- Viral diversity and host associations in microbial electrolysis cells.ISME communications · 2024Article
- Anaerobiosis, a neglected factor in phage-bacteria interactions.Applied and environmental microbiology · 2023Article
- Diverse electron carriers drive syntrophic interactions in an enriched anaerobic acetate-oxidizing consortium.The ISME journal · 2023Article
- Global diversity and biogeography of DNA viral communities in activated sludge systems.Microbiome · 2023Article
- Presence and role of viruses in anaerobic digestion of food waste under environmental variability.Microbiome · 2023Article
- Nonbacterial Microflora in Wastewater Treatment Plants: an Underappreciated Potential Source of Pathogens.Microbiology spectrum · 2023Article
- A Novel XRE-Type Regulator Mediates Phage Lytic Development and Multiple Host Metabolic Processes in Pseudomonas aeruginosa.Microbiology spectrum · 2022Article
- Analysis of the anaerobic digestion metagenome under environmental stresses stimulating prophage induction.Microbiome · 2022Article
- Article
- Heterogeneity of soil bacterial and bacteriophage communities in three rice agroecosystems and potential impacts of bacteriophage on nutrient cycling.Environmental microbiome · 2022Article
- Syntrophic propionate-oxidizing bacteria in methanogenic systems.FEMS microbiology reviews · 2022Review
- Microbiological insights into anaerobic digestion for biogas, hydrogen or volatile fatty acids (VFAs): a review.Bioengineered · 2022Review
- Phage Genome Diversity in a Biogas-Producing Microbiome Analyzed by Illumina and Nanopore GridION Sequencing.Microorganisms · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBacteriophage-prokaryote dynamics and interaction are believed to be important in governing microbiome composition and ecosystem functions, yet our limited knowledge of the spatial and temporal variation in phage and prokaryotic community compositions precludes accurate assessment of their roles and impacts. Anaerobic digesters are ideal model systems to examine phage-host interaction, owing to easy access, stable operation, nutrient-rich environment, and consequently enormous numbers of phages and prokaryotic cells.
resultsEquipped with high-throughput, cutting-edge environmental genomics techniques, we examined phage and prokaryotic community composition of four anaerobic digesters in full-scale wastewater treatment plants across China. Despite the relatively stable process performance in biogas production, phage and prokaryotic groups fluctuated monthly over a year of study period, showing significant correlations between those two groups at the α- and β-diversity levels. Strikingly, phages explained 40.6% of total variations of the prokaryotic community composition, much higher than the explanatory power by abiotic factors (14.5%). Consequently, phages were significantly (P < 0.010) linked to parameters related to process performance including biogas production and volatile solid concentrations. Association network analyses showed phage-prokaryote pairs were shallowly conserved since they were detected only within small viral clades.
conclusionsThose results collectively demonstrate phages as a major biotic factor in controlling prokaryotic composition and process performance. Therefore, phages may play a larger role in shaping prokaryotic community dynamics and process performance of anaerobic digesters than currently appreciated.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.