Trial reportSleep & breathing = Schlaf & Atmung2017
Effects of upper-airway stimulation on sleep architecture in patients with obstructive sleep apnea.
Trial report in Sleep & breathing = Schlaf & Atmung, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02293746 (Inspire® Upper Airway Stimulation), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Inspire® Upper Airway Stimulation (UAS) System German Post-Market Study: CE Certificate Number 562872
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Patient-reported outcomes with hypoglossal nerve stimulation for treatment of obstructive sleep apnea: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Pooled it
- Trial
- Patient-reported outcome: results of the multicenter German post-market study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018Trial
- Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis on Responder-Based Outcomes and Between-Study Heterogeneity.Journal of clinical medicine · 2026Review
- Ultrasonographic Assessment of Upper Airway Structures in Adult Obstructive Sleep Apnea: A Systematic Review.Journal of clinical medicine · 2026Review
- Post-operative radiological evaluation of a bilateral hypoglossal nerve stimulation system.Frontiers in surgery · 2026Article
- The potential impact of new remodelling intrapharynegal OSA surgery on sleep architecture: a preliminary investigation.Sleep & breathing = Schlaf & Atmung · 2024Article
- Surgical treatment for obstructive sleep apnea: effect on sleep architecture.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Observational
- International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023Review
- Hypoglossal nerve stimulation versus positive airway pressure therapy for obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2023Article
- Insomnia in Patients Undergoing Hypoglossal Nerve Stimulation Therapy for Obstructive Sleep Apnea.Biology · 2023Article
- Short-Term Outcome of Unilateral Inspiration-Coupled Hypoglossal Nerve Stimulation in Patients with Obstructive Sleep Apnea.International journal of environmental research and public health · 2022Article
- Factors affecting obstructive sleep apnea patients' use of upper airway stimulation treatment.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Obstruction level associated with outcome in hypoglossal nerve stimulation.Sleep & breathing = Schlaf & Atmung · 2022Article
- Hypoglossal Nerve Stimulation Therapy.Advances in experimental medicine and biology · 2022Article
- Changes in breath cycle sensing affect outcomes in upper airway stimulation in sleep apnea.Laryngoscope investigative otolaryngology · 2020Article
- Hypoglossal nerve stimulation therapy does not alter tongue protrusion strength and fatigability in obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020Article
- Bilateral hypoglossal nerve stimulation for treatment of adult obstructive sleep apnoea.The European respiratory journal · 2020Article
- REM sleep is associated with white matter integrity in cognitively healthy, older adults.PloS one · 2020Article
- Patient experience with upper airway stimulation in the treatment of obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSelective upper-airway stimulation (UAS) is a novel therapy for patients with obstructive sleep apnea (OSA). The aim of this study was to compare changes in sleep architecture during the diagnostic polysomnography and the post-implantation polysomnography in UAS in patients with OSA.
methodsTwenty-six patients who received a UAS device (Inspire Medical Systems) were included. Treatment outcome was evaluated 2 and 3 months after surgery. Data collection included demographics, body mass index (BMI), apnea hypopnea index (AHI), oxygen saturation and desaturation index (ODI), Epworth sleepiness score (ESS), arousal parameter, and sleep patterns.
resultsThe mean age was 60.2 years, 25 patients were male, 1 patient was female. Mean BMI was 29.0 kg/m
conclusionIn conclusion, significant changes in sleep architecture of patients with OSA and sufficient treatment with UAS could be observed. A reduction of the amount of time spent in N1-sleep could be caused by treatment with UAS and the rebound of REM sleep, observed for the first time in a study on UAS, is also a potential marker of the efficacy of UAS on sleep architecture.
trial registrationNCT02293746.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.