Trial reportEuropean journal of applied physiology2017
Cerebral oxygenation during cortical activation: the differential influence of three exercise training modalities. A randomized controlled trial.
Trial report in European journal of applied physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 6 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Can exercise combined with transcranial direct current stimulation improve cognitive function in older adults? A systematic review and meta-analysis.Frontiers in neuroscience · 2026Pooled it
- Exercise promotes brain health: a systematic review of fNIRS studies.Frontiers in psychology · 2024Pooled it
- The physiological mechanism and effect of resistance exercise on cognitive function in the elderly people.Frontiers in public health · 2022Pooled it
- The Effects of High-Intensity Interval Training (HIIT) on Fall Risk Factors in Healthy Older Adults: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Effects of Exercise Training Interventions on Executive Function in Older Adults: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2020Pooled it
- Effects of high intensity interval exercise on cerebrovascular function: A systematic review.PloS one · 2020Pooled it
- Trial
- Trial
- Feasibility of High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumor and Young Adults With Isocitrate Dehydrogenase-Mutant Gliomas (HYPE): Protocol for a Randomized Controlled Trial.JMIR research protocols · 2026Article
- Distinct neural mechanisms underlying the effects of agility and resistance-aerobic training on executive function and gait in young adults.Frontiers in psychology · 2026Article
- Research progress on exercise-induced executive function improvements in older adults: insights from functional near-infrared spectroscopy.Frontiers in psychology · 2026Review
- The relationship between muscle strength and working memory in older adults: fNIRS-based evidence.Frontiers in psychology · 2026Article
- Examining the predictive effect of physical activity, daily step count and perceived stress level on cognitive flexibility.Scientific reports · 2025Article
- Mechanisms of interventions targeting modifiable factors for dementia risk reduction.Molecular neurodegeneration · 2025Review
- Physical Activity to Counter Age-Related Cognitive Decline: Benefits of Aerobic, Resistance, and Combined Training-A Narrative Review.Sports medicine - open · 2025Review
- Exercise-mediated cerebrovascular repair in Alzheimer's disease: from pathophysiology to therapeutic precision.Frontiers in aging neuroscience · 2025Review
- Cerebral oxygenation during submaximal and peak exercise for sedentary adults with and without down syndrome.Frontiers in physiology · 2025Article
- Functional neuroplasticity of facilitation and interference effects on inhibitory control following 3-month physical exercise in aging.Scientific reports · 2024Article
- The Utility of High Intensity Interval Training to Improve Cognitive Aging in Heart Disease Patients.International journal of environmental research and public health · 2022Review
- Intense long-term training impairs brain health compared with moderate exercise: Experimental evidence and mechanisms.Annals of the New York Academy of Sciences · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine if a cerebral oxygenation response during cortical activation is influenced by exercise training mode.
methodsSixty-seven individuals (55-75 years old) volunteered for this 16-week intervention study. Participants were randomized into a resistance training (RT) group (n = 22), high-intensity interval training (HIIT) group (n = 13), moderate continuous training (MCT) group (n = 13) and a control (CON) group (n = 19). Near-infrared spectroscopy was used to measure cerebral oxygenation during the Stroop task. A submaximal Bruce treadmill test was used to measure changes in walking endurance.
resultsThe GROUP × TIME interaction for reaction time on the naming and executive Stroop conditions were not significant (P > 0.05). At post-test, the CON group showed increased brain activation, with significantly higher relative oxy-haemoglobin (O
conclusionSixteen weeks of exercise training resulted in more efficient cerebral oxygenation during cortical activation compared to a no-exercise control group. Furthermore, HIIT and MCT were superior to RT for task-efficient cerebral oxygenation and improved oxygen utilization during cortical activation in older individuals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.