ArticleOrthopaedic journal of sports medicine2017
Treatment of Subacromial Impingement Syndrome: Platelet-Rich Plasma or Exercise Therapy? A Randomized Controlled Trial.
Article in Orthopaedic journal of sports medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05248061 (Comparison of the Effects of Platelet-Rich Plasma Supplementary Exercise and Exercise Only on Pain, Muscle Strength, Functionality, and Quality of Life in Subacromial Impingement Syndrome), which is not on this map. Cited by 26 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison of the Effects of Platelet-Rich Plasma Supplementary Exercise and Exercise Only on Pain, Muscle Strength, Functionality, and Quality of Life in Subacromial Impingement Syndrome: A Randomized Controlled Study
Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- Platelet-rich plasma does not improve clinical results in patients with rotator cuff disorders but reduces the retear rate. A systematic review and meta-analysis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Pooled it
- Ultrasound-guided injection of platelet-rich plasma for tendinopathies: a systematic review and meta-analysis.Blood transfusion = Trasfusione del sangue · 2023Pooled it
- Platelet-rich plasma for rotator cuff tendinopathy: A systematic review and meta-analysis.PloS one · 2021Pooled it
- Efficacy of platelet-rich plasma as conservative treatment in orthopaedics: a systematic review and meta-analysis.Blood transfusion = Trasfusione del sangue · 2018Pooled it
- Effectiveness of lyophilized growth factors injection for subacromial impingement syndrome: a prospective randomized double-blind placebo-controlled study.Journal of orthopaedic surgery and research · 2023Trial
- Short-term outcomes of subacromial injection of combined corticosteroid with low-volume compared to high-volume local anesthetic for rotator cuff impingement syndrome: a randomized controlled non-inferiority trial.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2018Trial
- Rotator Cuff-Related Shoulder Pain: A Survey of Current Physiotherapy Practice in Cyprus.Clinics and practice · 2026Article
- Platelet rich plasma for treatment in the shoulder and elbow: a review of current literature.JSES reviews, reports, and techniques · 2025Review
- Autologous Peripheral Blood-Derived Orthobiologics for the Management of Shoulder Disorders: A Review of Current Clinical Evidence.Pain and therapy · 2025Review
- Accuracy of Two Methods in Estimating Target Muscle Force During Shoulder Submaximal Isometric Contractions.International journal of sports physical therapy · 2025Article
- The Effect of Platelet Dose on Outcomes after Platelet Rich Plasma Injections for Musculoskeletal Conditions: A Systematic Review and Meta-Analysis.Current reviews in musculoskeletal medicine · 2024Review
- Role of Image-guided Platelet-rich Plasma Injection in the Management of Patients of Supraspinatus Tendon Tear.Journal of orthopaedic case reports · 2024Article
- Clinical Effects of Additional Platelet-Rich Plasma Application to Exercise Therapy in Patients with Subacromial Impingement Syndrome: A Double-Blind Randomized Controlled Trial.Orthopaedic journal of sports medicine · 2024Article
- Shoulder specific exercise therapy is effective in reducing chronic shoulder pain: A network meta-analysis.PloS one · 2024Article
- Evidence-Based Clinical Practice Guidelines on Regenerative Medicine Treatment for Chronic Pain: A Consensus Report from a Multispecialty Working Group.Journal of pain research · 2024Review
- "Restoring That Faith in My Shoulder": A Qualitative Investigation of How and Why Exercise Therapy Influenced the Clinical Outcomes of Individuals With Rotator Cuff-Related Shoulder Pain.Physical therapy · 2023Article
- Review
- The role of platelet-rich plasma in shoulder pathologies: a critical review of the literature.EFORT open reviews · 2023Review
- Article
- Platelet-rich plasma versus corticosteroid injections for rotator cuff tendinopathy: a comparative study with up to 18-month follow-up.Clinics in shoulder and elbow · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSubacromial impingement syndrome (SAIS) is the most common disorder of the shoulder. The evidence for the effectiveness of treatment options is inconclusive and limited. Therefore, there is a need for more evidence in this regard, particularly for long-term outcomes. HYPOTHESIS: Platelet-rich plasma (PRP) would be an effective method in treating subacromial impingement. STUDY
designRandomized controlled trial; Level of evidence, 1.
methodsThis was a single-blinded randomized clinical trial with 1-, 3-, and 6-month follow-up. Sixty-two patients were randomly placed into 2 groups, receiving either PRP or exercise therapy. The outcome parameters were pain, shoulder range of motion (ROM), muscle force, functionality, and magnetic resonance imaging findings.
resultsBoth treatment options significantly reduced pain and increased shoulder ROM compared with baseline measurements. Both treatments also significantly improved functionality. However, the treatment choices were not significantly effective in improving muscle force. Trend analysis revealed that in the first and third months, exercise therapy was superior to PRP in pain, shoulder flexion and abduction, and functionality. However, in the sixth month, only shoulder abduction and total Western Ontario Rotator Cuff score were significantly different between the 2 groups.
conclusionBoth PRP injection and exercise therapy were effective in reducing pain and disability in patients with SAIS, with exercise therapy proving more effective.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.